Concepedia

Resection-mediated Rad51 Loading

Resection-Mediated Rad51 Loading is a molecular mechanism in homologous recombination whereby the 5'→3' nucleolytic resection of DNA double-strand break ends generates 3' single-stranded DNA overhangs that serve as platforms for the direct recruitment and loading of the Rad51 recombinase to initiate strand invasion and repair.

8

Publications

692

Citations

75

Authors

39

Institutions

Publications per year

2017–2026

3

Parents

Publications

8

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

Emma Bolderson, Nozomi Tomimatsu, Derek J. Richard et al. · Nucleic Acids Research · 2009 · 183 citations · Full text

, , +17

ATP‐driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling

Rajashree A. Deshpande, Gareth J. Williams, Oliver Limbo et al. · The EMBO Journal · 2014 · 144 citations · Full text

, , +16

ATP‐dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex

Yaqi Liu, Sihyun Sung, Youngran Kim et al. · The EMBO Journal · 2015 · 124 citations · Full text

, , +7

AID-Dependent Generation of Resected Double-Strand DNA Breaks and Recruitment of Rad52/Rad51 in Somatic Hypermutation

Hong Zan, Xiaoping Wu, Atsumasa Komori et al. · Immunity · 2003 · 85 citations · Full text

, , +16

Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast

Zhenxin Yan, Chaoyou Xue, Sandeep Kumar et al. · Molecular Cell · 2019 · 52 citations · Full text

, , +11

1–5 of 8

Authors

75

  1. XW
    Xiaoping Wu

    China Agricultural University, China

    1 publications · 85 citations

    1

    h-index

  2. ZT
    Zizhi Tang

    Sichuan University, China

    1 publications · 47 citations

    1

    h-index

  3. QH
    Qun He

    China Agricultural University, China

    1 publications · 47 citations

    1

    h-index

  4. MS
    Merula Stout

    University of Zurich, Switzerland

    1 publications · 27 citations

    1

    h-index

  5. CX
    Chaoyou Xue

    Columbia University, United States

    1 publications · 52 citations

    1

    h-index

1–5 of 75

Institutions

39

  1. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    2 h-index

    3 publications

    300 citations

  2. University of Sussex

    Brighton, United Kingdom

    2 h-index

    4 publications

    171 citations

  3. University of Zurich

    Zurich, Switzerland

    1 h-index

    3 publications

    81 citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    1 h-index

    4 publications

    576 citations

  5. National Institute of Environmental Health Sciences

    Durham, United States

    1 h-index

    1 publications

    144 citations

  6. Pohang TechnoPark (South Korea)

    Pohang, South Korea

    1 h-index

    2 publications

    248 citations

  7. Indiana University Bloomington

    Bloomington, United States

    1 h-index

    2 publications

    104 citations

  8. Pohang University of Science and Technology

    Pohang, South Korea

    1 h-index

    7 publications

    868 citations

1–8 of 39

Venues

  1. Nature Communications

    2 publications · 74 citations

    2

    h-index

  2. The EMBO Journal

    2 publications · 268 citations

    2

    h-index

  3. Immunity

    1 publications · 85 citations

    1

    h-index

  4. Molecular Cell

    1 publications · 52 citations

    1

    h-index

  5. Genome Instability & Disease

    GIAD · 1 publications · 30 citations

    1

    h-index

1–5