Hong Zan

B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids

Helia N. Sanchez, Justin B. Moroney, Huoqun Gan et al. · Nature Communications · 2020 · 334 citations · Full text

BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway

Egest J. Pone, Jinsong Zhang, Thach Mai et al. · Nature Communications · 2012 · 236 citations · Full text

CD40 Ligand and Appropriate Cytokines Induce Switching to IgG, IgA, and IgE and Coordinated Germinal Center and Plasmacytoid Phenotypic Differentiation in a Human Monoclonal IgM+IgD+ B Cell Line

Andrea Cerutti, Hong Zan, András Schaffer et al. · The Journal of Immunology · 1998 · 212 citations

Lymphocyte Development, Immune Regulation, Immunology +18

The Translesion DNA Polymerase ζ Plays a Major Role in Ig and bcl-6 Somatic Hypermutation

Hong Zan, Atsumasa Komori, Zongdong Li et al. · Immunity · 2001 · 205 citations · Full text

Chromatin, Bcl-6 Somatic Hypermutation, Somatic Variant +8

CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-beta: evidence for TGF-beta but not IL-10-dependent direct S mu-->S alpha and sequential S mu-->S gamma, S gamma-->S alpha DNA recombination.

Hong Zan, Andrea Cerutti, Patricia Dramitinos et al. · PubMed · 1998 · 155 citations

Lymphocyte Development, Adaptive Immune System, T-regulatory Cell +23