Concepedia

Replication Timing During Differentiation

Replication Timing During Differentiation is a biological regulatory phenomenon that refers to the programmed changes in the temporal order of DNA replication during cellular differentiation, distinguishing it from constitutive replication timing programs maintained across cell states.

20

Publications

2K

Citations

79

Authors

36

Institutions

Publications per year

2017–2026

0

Parents

Publications

20

Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types

Tyrone Ryba, Ichiro Hiratani, Junjie Lu et al. · Genome Research · 2010 · 647 citations · Full text

, , +17

Reversal of terminal differentiation and control of DNA replication: Cyclin A and cdk2 specifically localize at subnuclear sites of DNA replication

M. Cristina Cardoso, Heinrich Leonhardt, Bernardo Nadal‐Ginard · Cell · 1993 · 378 citations

, , +15

Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells

Juan Carlos Rivera‐Mulia, Quinton Buckley, Takayo Sasaki et al. · Genome Research · 2015 · 185 citations · Full text

, , +17

The Expression of Poly(ADP-ribose) Polymerase during Differentiation-Linked DNA Replication Reveals That It Is a Component of the Multiprotein DNA Replication Complex

Cynthia M. Simbulan‐Rosenthal, Dean S. Rosenthal, Helmuth Hilz et al. · Biochemistry · 1996 · 137 citations

, , +15

Differentiation-induced replication-timing changes are restricted to AT-rich/long interspersed nuclear element (LINE)-rich isochores

Ichiro Hiratani, Amanda Leskovar, David M. Gilbert · Proceedings of the National Academy of Sciences · 2004 · 115 citations

, , +14

1–5 of 20

Authors

79

  1. DM
    David M. Gilbert

    Florida State University, United States

    5 publications · 1K citations

    5

    h-index

  2. RF
    R.A. Flickinger

    University at Buffalo, State University of New York, United States

    3 publications · 97 citations

    3

    h-index

  3. IH
    Ichiro Hiratani

    RIKEN Center for Biosystems Dynamics Research, Japan

    3 publications · 785 citations

    3

    h-index

  4. TC
    Thomas C. Schulz

    University of Georgia, United States

    2 publications · 832 citations

    2

    h-index

  5. SD
    Stephen Dalton

    University of Georgia, United States

    2 publications · 832 citations

    2

    h-index

1–5 of 79

Institutions

36

  1. Florida State University

    Tallahassee, United States

    3 h-index

    17 publications

    5.1K citations

  2. University at Buffalo, State University of New York

    Buffalo, United States

    3 h-index

    6 publications

    230 citations

  3. ViaCyte (United States)

    San Diego, United States

    2 h-index

    4 publications

    1.7K citations

  4. SUNY Upstate Medical University

    Syracuse, United States

    2 h-index

    5 publications

    437 citations

  5. University of Georgia

    Athens, United States

    2 h-index

    5 publications

    1.8K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    1 h-index

    3 publications

    1.1K citations

  7. University of Maryland, Baltimore

    Baltimore, United States

    1 h-index

    9 publications

    1.2K citations

  8. The University of Osaka

    Osaka, Japan

    1 h-index

    2 publications

    58 citations

1–8 of 36

Venues

  1. Developmental Biology

    2 publications · 76 citations

    2

    h-index

  2. Genome Research

    GR · 2 publications · 832 citations

    2

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 186 citations

    2

    h-index

  4. Cell

    1 publications · 378 citations

    1

    h-index

  5. Journal of Theoretical Biology

    1 publications · 19 citations

    1

    h-index

1–5