Concepedia

Replication Origin Licensing

Replication Origin Licensing is the process by which pre-replication complexes are assembled at DNA replication origins during the G1 phase of the cell cycle, thereby conferring the potential for initiation of DNA replication in a regulated and once-per-cell-cycle manner.

153

Publications

13.1K

Citations

736

Authors

289

Institutions

Publications per year

2017–2026

41

Variants

Origin Licensing

Parents

Publications

153

Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1

Lyubomir T. Vassilev, Christian Tovar, Shaoqing Chen et al. · Proceedings of the National Academy of Sciences · 2006 · 824 citations · Full text

, , +17

Purification of an MCM-containing complex as a component of the DNA replication licensing system

J. Chong, Hiro Mahbubani, Chong-Yee Khoo et al. · Nature · 1995 · 358 citations

, , +13

The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome

Alex Kuo, Jikui Song, Peggie Cheung et al. · Nature · 2012 · 351 citations · Full text

, , +13

CDKs Promote DNA Replication Origin Licensing in Human Cells by Protecting Cdc6 from APC/C-Dependent Proteolysis

Niels Mailand, John F.X. Diffley · Cell · 2005 · 338 citations · Full text

, , +14

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Panagiotis Galanos, Konstantinos Vougas, David Walter et al. · Nature Cell Biology · 2016 · 312 citations · Full text

, , +16

1–5 of 153

Authors

736

  1. JJ
    J. Julian Blow

    University of Dundee, United Kingdom

    18 publications · 2.4K citations

    18

    h-index

  2. JG
    Jeanette Gowen Cook

    University of North Carolina at Chapel Hill, United States

    8 publications · 417 citations

    8

    h-index

  3. SP
    Stephen P. Bell

    Massachusetts Institute of Technology, United States

    8 publications · 333 citations

    8

    h-index

  4. JC
    J. Chong

    Agriculture and Agri-Food Canada, Canada

    7 publications · 1K citations

    7

    h-index

  5. PJ
    Peter J. Gillespie

    University of Dundee, United Kingdom

    6 publications · 468 citations

    6

    h-index

1–5 of 736

Institutions

289

  1. University of Dundee

    Dundee, United Kingdom

    17 h-index

    51 publications

    4.8K citations

  2. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    11 h-index

    40 publications

    2K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    46 publications

    2K citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    8 h-index

    25 publications

    1.1K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    21 publications

    1.1K citations

  6. Cancer Research UK

    London, United Kingdom

    6 h-index

    13 publications

    1.8K citations

  7. Wellcome Trust

    London, United Kingdom

    6 h-index

    16 publications

    1.9K citations

  8. Brandeis University

    Waltham, United States

    6 h-index

    11 publications

    421 citations

1–8 of 289

Venues

  1. Nucleic Acids Research

    11 publications · 420 citations

    11

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 1.4K citations

    9

    h-index

  3. Journal of Biological Chemistry

    JBC · 8 publications · 643 citations

    8

    h-index

  4. Nature

    8 publications · 1.6K citations

    8

    h-index

  5. Molecular Cell

    7 publications · 1.1K citations

    7

    h-index

1–5