Concepedia

Replication Conflicts

Replication Conflicts is a theoretical construct in molecular biology that denotes the phenomenon wherein opposing DNA replication and transcription machineries interact on the same chromosomal region, leading to steric hindrance, genomic instability, and potential disruption of DNA synthesis fidelity.

51

Publications

2.5K

Citations

384

Authors

142

Institutions

Publications per year

2017–2026

44

Variants

Replication-transcription Conflicts

Parents

Publications

51

The Transcription Factor DksA Prevents Conflicts between DNA Replication and Transcription Machinery

Ashley K. Tehranchi, Matthew D. Blankschien, Yan Zhang et al. · Cell · 2010 · 151 citations · Full text

, , +14

Accelerated gene evolution through replication–transcription conflicts

Sandip Paul, Samuel Million‐Weaver, Sujay Chattopadhyay et al. · Nature · 2013 · 147 citations

, , +12

Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

Jérôme Poli, Christian‐Benedikt Gerhold, Alessandro Tosi et al. · Genes & Development · 2016 · 141 citations · Full text

, , +17

Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide

Olivier Brison, Sami El Hilali, Dana Azar et al. · Nature Communications · 2019 · 111 citations · Full text

, , +17

Chromatin conformation regulates the coordination between DNA replication and transcription

Ricardo Almeida, José Miguel Fernández-Justel, Cristina Santa-María et al. · Nature Communications · 2018 · 104 citations · Full text

, , +17

1–5 of 51

Authors

384

  1. HM
    Houra Merrikh

    University of Washington, United States

    6 publications · 450 citations

    6

    h-index

  2. AA
    Andrés Aguilera

    Universidad de Sevilla, Spain

    4 publications · 143 citations

    4

    h-index

  3. EY
    Emily Yun‐Chia Chang

    University of British Columbia, Canada

    3 publications · 189 citations

    3

    h-index

  4. JP
    James P. Wells

    University of British Columbia, Canada

    3 publications · 189 citations

    3

    h-index

  5. JU
    Juachi U. Dimude

    Brunel University of London, United Kingdom

    3 publications · 121 citations

    3

    h-index

1–5 of 384

Institutions

142

  1. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    23 publications

    1.7K citations

  2. Centro Andaluz de Biología Molecular y Medicina Regenerativa

    Seville, Spain

    4 h-index

    14 publications

    516 citations

  3. Universidad de Sevilla

    Seville, Spain

    4 h-index

    14 publications

    516 citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    5 publications

    224 citations

  5. University of Washington

    Seattle, United States

    4 h-index

    10 publications

    1.1K citations

  6. University of British Columbia

    Vancouver, Canada

    4 h-index

    7 publications

    348 citations

  7. University of Nottingham

    Nottingham, United Kingdom

    3 h-index

    3 publications

    94 citations

  8. Université Paris-Saclay

    Gif-sur-Yvette, France

    3 h-index

    7 publications

    356 citations

1–8 of 142

Venues

  1. Nature Communications

    10 publications · 660 citations

    10

    h-index

  2. Nucleic Acids Research

    5 publications · 169 citations

    5

    h-index

  3. PLoS Genetics

    4 publications · 168 citations

    4

    h-index

  4. Cell Reports

    4 publications · 211 citations

    4

    h-index

  5. Nature

    3 publications · 256 citations

    3

    h-index

1–5