Concepedia

Replication Checkpoint Adaptation

Replication Checkpoint Adaptation is a regulatory mechanism in the DNA damage response pathway that enables cells to resume the cell cycle despite unresolved replication stress by attenuating checkpoint signaling, thereby distinguishing it from sustained checkpoint activation or checkpoint recovery mechanisms.

15

Publications

1K

Citations

100

Authors

52

Institutions

Publications per year

2017–2026

9

Parents

Publications

15

PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells

Annabel Quinet, Stephanie Tirman, Jessica Jackson et al. · Molecular Cell · 2019 · 273 citations · Full text

, , +16

Adaptation of a DNA Replication Checkpoint Response Depends upon Inactivation of Claspin by the Polo-like Kinase

Hae Yong Yoo, Akiko Kumagai, Anna Shevchenko et al. · Cell · 2004 · 221 citations · Full text

, , +15

Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner

Julien N Bianco, Valérie Bergoglio, Yea‐Lih Lin et al. · Nature Communications · 2019 · 161 citations · Full text

, , +17

Cancer cells that survive checkpoint adaptation contain micronuclei that harbor damaged DNA

Cody W. Lewis, Roy M. Golsteyn · Cell Cycle · 2016 · 58 citations · Full text

, , +17

The DNA Replication Checkpoint Directly Regulates MBF-Dependent G<sub>1</sub>/S Transcription

Chaitali Dutta, Prasanta K. Patel, Adam P. Rosebrock et al. · Molecular and Cellular Biology · 2008 · 55 citations

, , +17

1–5 of 15

Authors

100

  1. HN
    Hemalatha Narassimprakash

    Centre National de la Recherche Scientifique, France

    2 publications · 45 citations

    2

    h-index

  2. DC
    Diletta Ciardo

    Commissariat à l'Énergie Atomique et aux Énergies Alternatives, France

    2 publications · 45 citations

    2

    h-index

  3. AG
    Arach Goldar

    Commissariat à l'Énergie Atomique et aux Énergies Alternatives, France

    2 publications · 45 citations

    2

    h-index

  4. JH
    Jean‐Sébastien Hoffmann

    Centre National de la Recherche Scientifique, France

    2 publications · 187 citations

    2

    h-index

  5. MP
    Marie‐Jeanne Pillaire

    Centre National de la Recherche Scientifique, France

    2 publications · 187 citations

    2

    h-index

1–5 of 100

Institutions

52

  1. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    25 publications

    1.8K citations

  2. Inserm

    Paris, France

    3 h-index

    7 publications

    586 citations

  3. Université Paris-Saclay

    Gif-sur-Yvette, France

    2 h-index

    12 publications

    270 citations

  4. Medical Research Council

    London, United Kingdom

    2 h-index

    4 publications

    620 citations

  5. CEA Paris-Saclay

    Gif-sur-Yvette, France

    2 h-index

    12 publications

    270 citations

  6. Commissariat à l'Énergie Atomique et aux Énergies Alternatives

    Paris, France

    2 h-index

    12 publications

    270 citations

  7. Centre de Recherches en Cancérologie de Toulouse

    Toulouse, France

    2 h-index

    6 publications

    561 citations

  8. Institut de Biologie Intégrative de la Cellule

    Gif-sur-Yvette, France

    2 h-index

    12 publications

    270 citations

1–8 of 52

Venues

  1. Cell Cycle

    2 publications · 78 citations

    2

    h-index

  2. Molecular Cell

    2 publications · 305 citations

    2

    h-index

  3. BioMed Research International

    1 publications · 28 citations

    1

    h-index

  4. Nature Communications

    1 publications · 161 citations

    1

    h-index

  5. DNA repair

    1 publications · 19 citations

    1

    h-index

1–5