Concepedia

Repeat Protein Engineering

Repeat Protein Engineering is a method in protein scaffold engineering that involves the rational design and optimization of tandemly repeated structural motifs to generate novel binding proteins with enhanced stability and specificity.

43

Publications

3.8K

Citations

232

Authors

71

Institutions

Publications per year

2017–2026

14

Parents

Publications

43

A synthetic IgG-binding domain based on staphylococcal protein A

Björn Nilsson, Tomas Moks, Birger Jansson et al. · Protein Engineering Design and Selection · 1987 · 762 citations

, , +13

Designing Repeat Proteins: Well-expressed, Soluble and Stable Proteins from Combinatorial Libraries of Consensus Ankyrin Repeat Proteins

Hans Binz, Michael T. Stumpp, Patrik Forrer et al. · Journal of Molecular Biology · 2003 · 585 citations

, , +16

A repeat protein links Rubisco to form the eukaryotic carbon-concentrating organelle

Luke C. M. Mackinder, Moritz T. Meyer, Tabea Mettler‐Altmann et al. · Proceedings of the National Academy of Sciences · 2016 · 290 citations · Full text

, , +17

A Designed Ankyrin Repeat Protein Evolved to Picomolar Affinity to Her2

Christian Zahnd, Emanuel Wyler, Jochen M. Schwenk et al. · Journal of Molecular Biology · 2007 · 254 citations

, , +12

Engineering RNA sequence specificity of Pumilio repeats

Cheom‐Gil Cheong, Traci M. Tanaka Hall · Proceedings of the National Academy of Sciences · 2006 · 237 citations · Full text

, , +17

1–5 of 43

Authors

232

  1. AP
    Andreas Plückthun

    University of Zurich, Switzerland

    8 publications · 1.2K citations

    8

    h-index

  2. AL
    Aitziber L. Cortajarena

    CIC biomaGUNE, Spain

    4 publications · 123 citations

    4

    h-index

  3. FP
    Fabio Parmeggiani

    University of Washington, United States

    3 publications · 204 citations

    3

    h-index

  4. DB
    David Baker

    University of Washington, United States

    3 publications · 206 citations

    3

    h-index

  5. HK
    Hak‐Sung Kim

    Korea Advanced Institute of Science and Technology, South Korea

    3 publications · 193 citations

    2

    h-index

1–5 of 232

Institutions

71

  1. University of Zurich

    Zurich, Switzerland

    8 h-index

    41 publications

    5.8K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    4 h-index

    23 publications

    1.5K citations

  3. CIC biomaGUNE

    Donostia / San Sebastian, Spain

    4 h-index

    14 publications

    395 citations

  4. University of Washington

    Seattle, United States

    4 h-index

    24 publications

    1.1K citations

  5. Ikerbasque

    Bilbao, Spain

    4 h-index

    5 publications

    158 citations

  6. Korea Advanced Institute of Science and Technology

    Daejeon, South Korea

    3 h-index

    20 publications

    979 citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    4 publications

    235 citations

  8. Madrid Institute for Advanced Studies

    Madrid, Spain

    3 h-index

    6 publications

    198 citations

1–8 of 71

Venues

  1. Journal of Molecular Biology

    JMB · 8 publications · 1.3K citations

    8

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 798 citations

    6

    h-index

  3. PLoS ONE

    2 publications · 44 citations

    2

    h-index

  4. Angewandte Chemie International Edition

    2 publications · 46 citations

    2

    h-index

  5. Chemical Science

    2 publications · 36 citations

    2

    h-index

1–5