Concepedia

Renal Cystogenesis

Renal Cystogenesis is a pathophysiological process denoting the formation and development of fluid-filled epithelial-lined cysts within the renal parenchyma, distinguished from related mechanisms by its initiation from tubular basement membrane disruptions and subsequent dysregulation of epithelial cell proliferation, fluid secretion, and extracellular matrix remodeling in nephron segments.

372

Publications

26.1K

Citations

1.8K

Authors

451

Institutions

Publications per year

2017–2026

79

Parents

Publications

372

The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

Jonathan M. Shillingford, Noel Murcia, Claire H. Larson et al. · Proceedings of the National Academy of Sciences · 2006 · 798 citations · Full text

, , +15

Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

Fangming Lin, Thomas Hiesberger, Kimberly R. Cordes et al. · Proceedings of the National Academy of Sciences · 2003 · 585 citations

, , +17

Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function

Iain A. Drummond, Årindam Majumdar, Hartmut Hentschel et al. · Development · 1998 · 490 citations

, , +17

Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity

Katharina Hopp, Christopher J. Ward, Cynthia J. Hommerding et al. · Journal of Clinical Investigation · 2012 · 451 citations · Full text

, , +16

A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

Klaus Piontek, Luís F. Menezes, Miguel A. García-González et al. · Nature Medicine · 2007 · 421 citations

, , +13

1–5 of 372

Authors

1.8K

  1. PC
    Peter C. Harris

    Mayo Clinic, United States

    15 publications · 1.9K citations

    15

    h-index

  2. DP
    Darren P. Wallace

    University of Kansas Medical Center, United States

    15 publications · 647 citations

    13

    h-index

  3. SS
    Stefan Somlo

    Yale University, United States

    13 publications · 2.4K citations

    12

    h-index

  4. DJ
    Dorien J.M. Peters

    Leiden University Medical Center, Netherlands

    13 publications · 1.3K citations

    12

    h-index

  5. VE
    Vicente E. Torres

    Mayo Clinic, United States

    11 publications · 1.7K citations

    11

    h-index

1–5 of 1.8K

Institutions

451

  1. Yale University

    New Haven, United States

    21 h-index

    69 publications

    11.2K citations

  2. University of Kansas Medical Center

    Kansas City, United States

    20 h-index

    96 publications

    5.8K citations

  3. Mayo Clinic

    Rochester, United States

    18 h-index

    74 publications

    7.8K citations

  4. Harvard University

    Cambridge, United States

    17 h-index

    62 publications

    4.6K citations

  5. Johns Hopkins University

    Baltimore, United States

    15 h-index

    66 publications

    11.2K citations

  6. Johns Hopkins Medicine

    Baltimore, United States

    13 h-index

    53 publications

    10.7K citations

  7. University of Alabama at Birmingham

    Birmingham, United States

    12 h-index

    32 publications

    1.6K citations

  8. Leiden University Medical Center

    Leiden, The Netherlands

    12 h-index

    42 publications

    4.6K citations

1–8 of 451

Venues

  1. Journal of the American Society of Nephrology

    59 publications · 5.4K citations

    43

    h-index

  2. American Journal of Physiology-Renal Physiology

    38 publications · 1.7K citations

    25

    h-index

  3. Kidney International

    24 publications · 1.6K citations

    22

    h-index

  4. Human Molecular Genetics

    19 publications · 2.8K citations

    18

    h-index

  5. PubMed

    Repository · 16 publications · 643 citations

    13

    h-index

1–5