Concepedia

Regional Toxicity

Regional Toxicity is a clinical phenomenon characterized by adverse biological effects confined to a specific anatomical region following the administration of chemotherapeutic agents, distinguished from systemic toxicity by its localized manifestation and restricted physiological impact.

28

Publications

1.2K

Citations

122

Authors

37

Institutions

Publications per year

2017–2026

0

Parents

Publications

28

Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: results of a tumor necrosis factor dose-escalation study.

Douglas L. Fraker, H. Richard Alexander, Mary P. Andrich et al. · Journal of Clinical Oncology · 1996 · 212 citations

, , +17

Regional cancer chemotherapy.

Ensminger Wd, Gyves Jw · PubMed · 1984 · 93 citations

, , +16

Phase I and II trial of five-day infused 5-fluorouracil and radiation in advanced cancer of the head and neck.

J.E. Byfield, Thomas R. Sharp, Sallie S. Frankel et al. · Journal of Clinical Oncology · 1984 · 70 citations

, , +16

Regional toxicity after isolated limb perfusion with melphalan and tumour necrosis factor- α versus toxicity after melphalan alone

B. C. Vrouenraets, A.M.M. Eggermont, Andrew Hart et al. · European Journal of Surgical Oncology · 2001 · 60 citations

, , +8

Predictive Factors of Regional Toxicity and Serum Creatine Phosphokinase Levels After Isolated Limb Infusion for Melanoma: A Multi-Institutional Analysis

Alfredo A. Santillan, Keith A. Delman, Georgia M. Beasley et al. · Annals of Surgical Oncology · 2009 · 54 citations

, , +10

1–5 of 28

Authors

122

  1. JM
    Joost M. Klaase

    Medisch Spectrum Twente, Netherlands

    5 publications · 178 citations

    5

    h-index

  2. OE
    Omgo E. Nieweg

    The Netherlands Cancer Institute, Netherlands

    4 publications · 149 citations

    4

    h-index

  3. JF
    John F. Thompson

    Royal Prince Alfred Hospital, Australia

    4 publications · 179 citations

    4

    h-index

  4. BC
    B. C. Vrouenraets

    The Netherlands Cancer Institute, Netherlands

    4 publications · 130 citations

    4

    h-index

  5. PK
    Peter Kam

    Royal Prince Alfred Hospital, Australia

    3 publications · 130 citations

    3

    h-index

1–5 of 122

Institutions

37

  1. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    6 h-index

    26 publications

    919 citations

  2. The University of Sydney

    Sydney, Australia

    4 h-index

    11 publications

    417 citations

  3. Royal Prince Alfred Hospital

    Sydney, Australia

    4 h-index

    11 publications

    465 citations

  4. Rotterdam University of Applied Sciences

    Rotterdam, Netherlands

    3 h-index

    8 publications

    258 citations

  5. National Cancer Institute

    Bethesda, United States

    3 h-index

    3 publications

    311 citations

  6. National Institutes of Health

    Bethesda, United States

    3 h-index

    9 publications

    581 citations

  7. University of Miyazaki Hospital

    Miyazaki, Japan

    1 h-index

    1 publications

    35 citations

  8. University of Mississippi

    Oxford, United States

    1 h-index

    3 publications

    63 citations

1–8 of 37

Venues

  1. PubMed

    Repository · 7 publications · 312 citations

    7

    h-index

  2. Melanoma Research

    3 publications · 70 citations

    3

    h-index

  3. Annals of Surgical Oncology

    3 publications · 135 citations

    3

    h-index

  4. Cancer

    2 publications · 64 citations

    2

    h-index

  5. Journal of Clinical Oncology

    2 publications · 282 citations

    2

    h-index

1–5