Concepedia

Recombination-based Shuffling

Recombination-Based Shuffling is a computational method within iterative selection cycles that integrates genetic recombination principles to systematically rearrange and recombine constituent elements of candidate solutions, thereby generating novel variants while preserving structural coherence and enhancing search efficiency in solution space exploration.

8

Publications

484

Citations

24

Authors

13

Institutions

Publications per year

2017–2026

1

Parents

Publications

8

Optimization of DNA shuffling for high fidelity recombination

Huimin Zhao · Nucleic Acids Research · 1997 · 223 citations · Full text

, , +16

L-SCRaMbLE as a tool for light-controlled Cre-mediated recombination in yeast

Lena Hochrein, Leslie A. Mitchell, Karina Schulz et al. · Nature Communications · 2018 · 113 citations · Full text

, , +17

Staggered Extension Process (StEP) In Vitro Recombination

Anna Marie Aguinaldo, Frances H. Arnold · Humana Press eBooks · 2003 · 37 citations

, , +17

Synthetic shuffling and in vitro selection reveal the rugged adaptive fitness landscape of a kinase ribozyme

Edward A. Curtis, David P. Bartel · RNA · 2013 · 34 citations · Full text

, , +16

In vitro DNA recombination by L-Shuffling during ribosome display affinity maturation of an anti-Fas antibody increases the population of improved variants

Matthieu Chodorge, Laurent Fourage, Gilles Ravot et al. · Protein Engineering Design and Selection · 2008 · 29 citations · Full text

, , +16

1–5 of 8

Authors

24

  1. AM
    Anna Marie Aguinaldo

    California Institute of Technology, United States

    2 publications · 48 citations

    2

    h-index

  2. FH
    Frances H. Arnold

    California Institute of Technology, United States

    2 publications · 48 citations

    2

    h-index

  3. DK
    Dingyue Khor

    University of British Columbia, Canada

    1 publications · 20 citations

    1

    h-index

  4. GR
    Gilles Ravot

    Sanofi (France), France

    1 publications · 29 citations

    1

    h-index

  5. DS
    Deepak Sharma

    Institute of Microbial Technology, India

    1 publications · 20 citations

    1

    h-index

1–5 of 24

Institutions

13

  1. California Institute of Technology

    Pasadena, United States

    3 h-index

    4 publications

    308 citations

  2. Massachusetts Institute of Technology

    Cambridge, United States

    1 h-index

    2 publications

    68 citations

  3. Centro de Biología Molecular Severo Ochoa

    Madrid, Spain

    1 h-index

    1 publications

    17 citations

  4. Whitehead Institute for Biomedical Research

    Cambridge, United States

    1 h-index

    2 publications

    68 citations

  5. Universität Greifswald

    Greifswald, Germany

    1 h-index

    2 publications

    34 citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    1 h-index

    2 publications

    68 citations

  7. Universidad Autónoma de Madrid

    Madrid, Spain

    1 h-index

    1 publications

    17 citations

  8. Harvard University

    Cambridge, United States

    1 h-index

    1 publications

    34 citations

1–8 of 13

Venues

  1. Humana Press eBooks

    Ebook platform · 2 publications · 48 citations

    2

    h-index

  2. RNA

    1 publications · 34 citations

    1

    h-index

  3. Protein Science

    PS · 1 publications · 20 citations

    1

    h-index

  4. Nature Communications

    1 publications · 113 citations

    1

    h-index

  5. Protein Engineering Design and Selection

    PEDS · 1 publications · 29 citations

    1

    h-index

1–5