Concepedia

Recombination Efficiency Optimization

Recombination Efficiency Optimization is a methodological framework in molecular biology that systematically enhances the precision, rate, and specificity of site-specific recombination events by modulating enzymatic, sequence, and environmental parameters.

35

Publications

2.1K

Citations

160

Authors

78

Institutions

Publications per year

2017–2026

12

Parents

Publications

35

High-Efficiency FLP and ΦC31 Site-Specific Recombination in Mammalian Cells

Christopher S. Raymond, Philippe Soriano · PLoS ONE · 2007 · 401 citations · Full text

, , +16

Optimized second-generation CRY2–CIB dimerizers and photoactivatable Cre recombinase

Amir Taslimi, Brian D. Zoltowski, Jose G. Miranda et al. · Nature Chemical Biology · 2016 · 258 citations

, , +6

Probing Cellular Processes with Oligo-Mediated Recombination and Using the Knowledge Gained to Optimize Recombineering

James A. Sawitzke, Nina Costantino, Xintian Li et al. · Journal of Molecular Biology · 2011 · 169 citations · Full text

, , +16

Modeling Disease in Human ESCs Using an Efficient BAC-Based Homologous Recombination System

Hoseok Song, Sun-Ku Chung, Yang Xu · Cell stem cell · 2010 · 165 citations · Full text

, , +11

An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase

Andrea Kranz, Jun Fu, Kristin Duerschke et al. · genesis · 2010 · 161 citations

, , +14

1–5 of 35

Authors

160

  1. PP
    Pamela Peralta‐Yahya

    Georgia Institute of Technology, United States

    2 publications · 46 citations

    2

    h-index

  2. JF
    Jun Fu

    Technische Universität Dresden, Germany

    2 publications · 223 citations

    2

    h-index

  3. AF
    A. Francis Stewart

    Technische Universität Dresden, Germany

    2 publications · 223 citations

    2

    h-index

  4. VW
    Virginia W. Cornish

    Columbia University, United States

    2 publications · 46 citations

    2

    h-index

  5. AN
    Aleksandra Nivina

    Institut Pasteur, France

    1 publications · 26 citations

    1

    h-index

1–5 of 160

Institutions

78

  1. Columbia University

    New York, United States

    2 h-index

    8 publications

    184 citations

  2. Max Planck Institute of Molecular Cell Biology and Genetics

    Dresden, Germany

    2 h-index

    5 publications

    409 citations

  3. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    5 publications

    108 citations

  4. Technische Universität Dresden

    Dresden, Germany

    2 h-index

    10 publications

    1.2K citations

  5. Saarland University

    Saarbrücken, Germany

    1 h-index

    1 publications

    62 citations

  6. United States Department of Agriculture

    Washington, United States

    1 h-index

    2 publications

    56 citations

  7. Maine Medical Center Research Institute

    Scarborough, United States

    1 h-index

    6 publications

    72 citations

  8. Eastern Virginia Medical School

    Norfolk, United States

    1 h-index

    1 publications

    13 citations

1–8 of 78

Venues

  1. PLoS ONE

    3 publications · 443 citations

    3

    h-index

  2. Gene

    2 publications · 59 citations

    2

    h-index

  3. Journal of Molecular Biology

    JMB · 2 publications · 229 citations

    2

    h-index

  4. Nucleic Acids Research

    2 publications · 171 citations

    2

    h-index

  5. ACS Synthetic Biology

    2 publications · 37 citations

    2

    h-index

1–5