Concepedia

Recoded Genomes

Recoded Genomes is a genomic engineering construct in which the genetic code of an organism is systematically altered by reassigning one or more codons to enable orthogonal biological functions, thereby insulating engineered biological systems from natural ones.

13

Publications

1.7K

Citations

132

Authors

48

Institutions

Publications per year

2017–2026

6

Parents

Publications

13

Total synthesis of Escherichia coli with a recoded genome

Julius Fredens, Kaihang Wang, Daniel de la Torre et al. · Nature · 2019 · 538 citations · Full text

, , +15

Design, synthesis, and testing toward a 57-codon genome

Nili Ostrov, Matthieu Landon, Marc Güell et al. · Science · 2016 · 300 citations · Full text

, , +17

Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids

Miriam Amiram, Adrian D. Haimovich, Chenguang Fan et al. · Nature Biotechnology · 2015 · 290 citations · Full text

, , +17

Adaptive evolution of genomically recoded <i>Escherichia coli</i>

Timothy M. Wannier, Aditya M. Kunjapur, Daniel P. Rice et al. · Proceedings of the National Academy of Sciences · 2018 · 109 citations · Full text

, , +17

Ancient Genomes, Wise Bodies, Unhealthy People: Limits of a Genetic Paradigm in Biology and Medicine

Richard C. Strohman · Perspectives in biology and medicine · 1993 · 107 citations

, , +14

1–5 of 13

Authors

132

  1. GM
    George M. Church

    Harvard University, United States

    3 publications · 470 citations

    3

    h-index

  2. DS
    Dieter Söll

    Yale University, United States

    2 publications · 351 citations

    2

    h-index

  3. FJ
    Farren J. Isaacs

    Yale University, United States

    2 publications · 351 citations

    2

    h-index

  4. ML
    Matthieu Landon

    Harvard University, United States

    2 publications · 361 citations

    2

    h-index

  5. AE
    Andrew E. Firth

    University of Cambridge, United Kingdom

    2 publications · 109 citations

    2

    h-index

1–5 of 132

Institutions

48

  1. Harvard University

    Cambridge, United States

    6 h-index

    59 publications

    7.6K citations

  2. Center for Systems Biology

    Boston, United States

    3 h-index

    11 publications

    1K citations

  3. University College Cork

    Cork, Ireland

    2 h-index

    9 publications

    513 citations

  4. École Nationale Supérieure des Mines de Paris

    Paris, France

    2 h-index

    2 publications

    361 citations

  5. Yale University

    New Haven, United States

    2 h-index

    14 publications

    3.4K citations

  6. University College Dublin

    Dublin, Ireland

    1 h-index

    6 publications

    372 citations

  7. University of Cambridge

    Cambridge, United Kingdom

    1 h-index

    1 publications

    47 citations

  8. Lawrence Berkeley National Laboratory

    Berkeley, United States

    1 h-index

    5 publications

    100 citations

1–8 of 48

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 170 citations

    2

    h-index

  2. Nucleic Acids Research

    2 publications · 133 citations

    2

    h-index

  3. Cell Reports

    1 publications · 90 citations

    1

    h-index

  4. Nature

    1 publications · 538 citations

    1

    h-index

  5. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 1 publications · 20 citations

    1

    h-index

1–5