Concepedia

Receptor Sensitization

Receptor Sensitization is a regulatory phenomenon in which a cell's response to a ligand is enhanced through an increase in receptor responsiveness or signaling efficiency, distinguishing it from related processes such as upregulation or desensitization by emphasizing functional amplification rather than receptor quantity or tolerance changes.

68

Publications

4.4K

Citations

282

Authors

115

Institutions

Publications per year

2017–2026

6

Parents

Publications

68

Transient neuronal inhibition reveals opposing roles of indirect and direct pathways in sensitization

Susan M. Ferguson, Daniel Eskenazi, Masago Ishikawa et al. · Nature Neuroscience · 2010 · 424 citations · Full text

, , +11

Polyglutamine-expanded Huntingtin Promotes Sensitization of N-Methyl-d-aspartate Receptors via Post-synaptic Density 95

Sun Ying, Anneli Savanenin, P. Hemachandra Reddy et al. · Journal of Biological Chemistry · 2001 · 289 citations · Full text

, , +15

Desensitization of Capsaicin-activated Currents in the Vanilloid Receptor TRPV1 Is Decreased by the Cyclic AMP-dependent Protein Kinase Pathway

Durga P. Mohapatra, Carla Nau · Journal of Biological Chemistry · 2003 · 264 citations · Full text

, , +17

Investigation of the role of TRPV1 receptors in acute and chronic nociceptive processes using gene-deficient mice

Kata Bölcskei, Zsuzsanna Helyes, Árpád Szabó et al. · Pain · 2005 · 258 citations

, , +17

A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1

Ning Zhang, Sadeet Inan, Alan Cowan et al. · Proceedings of the National Academy of Sciences · 2005 · 246 citations · Full text

, , +17

1–5 of 68

Authors

282

  1. VJ
    Val J. Watts

    Purdue University West Lafayette, United States

    4 publications · 213 citations

    4

    h-index

  2. LO
    Laurence O. Trussell

    Vollum Institute, United States

    3 publications · 293 citations

    3

    h-index

  3. CF
    Charles F. Zorumski

    Washington University in St. Louis, United States

    3 publications · 293 citations

    3

    h-index

  4. LL
    Liu Lin Thio

    Washington University in St. Louis, United States

    3 publications · 293 citations

    3

    h-index

  5. GD
    G D Fischbach

    Washington University in St. Louis, United States

    3 publications · 293 citations

    3

    h-index

1–5 of 282

Institutions

115

  1. The University of Texas Medical Branch at Galveston

    Galveston, United States

    4 h-index

    11 publications

    355 citations

  2. Purdue University West Lafayette

    West Lafayette, United States

    3 h-index

    5 publications

    171 citations

  3. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    3 h-index

    12 publications

    344 citations

  4. Washington University in St. Louis

    St Louis, United States

    3 h-index

    12 publications

    1.2K citations

  5. Universidad de Buenos Aires

    Buenos Aires, Argentina

    2 h-index

    9 publications

    273 citations

  6. Harvard University

    Cambridge, United States

    2 h-index

    2 publications

    95 citations

  7. Friedrich-Alexander-Universität Erlangen-Nürnberg

    Erlangen, Germany

    2 h-index

    4 publications

    548 citations

  8. The University of Texas Southwestern Medical Center

    Dallas, United States

    2 h-index

    7 publications

    487 citations

1–8 of 115

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 661 citations

    6

    h-index

  2. Journal of Biological Chemistry

    JBC · 5 publications · 718 citations

    5

    h-index

  3. 4

    h-index

  4. PubMed

    Repository · 3 publications · 114 citations

    3

    h-index

  5. British Journal of Pharmacology

    BJP · 3 publications · 245 citations

    3

    h-index

1–5