Concepedia

Real-space Refinement

Real-Space Refinement is a computational methodology in structural biology that optimizes atomic models by iteratively adjusting their coordinates directly in real space, as opposed to reciprocal space, to better fit experimental density maps while preserving stereochemical accuracy.

70

Publications

42.3K

Citations

423

Authors

117

Institutions

Publications per year

2017–2026

9

Parents

Publications

70

Features and development of <i>Coot</i>

Paul Emsley, Bernhard Lohkamp, W. G. Scott et al. · Acta Crystallographica Section D Biological Crystallography · 2010 · 29.6K citations · Full text

, , +16

Real-space refinement in <i>PHENIX</i> for cryo-EM and crystallography

Pavel V. Afonine, Billy K. Poon, Randy J. Read et al. · Acta Crystallographica Section D Structural Biology · 2018 · 3.7K citations · Full text

, , +15

PDFfit2 and PDFgui: computer programs for studying nanostructure in crystals

Christopher L. Farrow, Pavol Juhás, Jie Liu et al. · Journal of Physics Condensed Matter · 2007 · 1.9K citations

, , +16

Critic2: A program for real-space analysis of quantum chemical interactions in solids

Alberto Otero‐de‐la‐Roza, Erin R. Johnson, Vı́ctor Luaña · Computer Physics Communications · 2013 · 817 citations · Full text

, , +14

Refinement of severely incomplete structures with maximum likelihood in<i>BUSTER–TNT</i>

Eric Blanc, Pietro Roversi, Clemens Vonrhein et al. · Acta Crystallographica Section D Biological Crystallography · 2004 · 722 citations · Full text

, , +16

1–5 of 70

Authors

423

  1. PE
    Paul Emsley

    MRC Laboratory of Molecular Biology, United Kingdom

    5 publications · 30.5K citations

    5

    h-index

  2. MS
    Michael S. Chapman

    Florida State University, United States

    4 publications · 263 citations

    4

    h-index

  3. MU
    Martin U. Schmidt

    Goethe University Frankfurt, Germany

    3 publications · 72 citations

    3

    h-index

  4. PV
    Pavel V. Afonine

    Lawrence Berkeley National Laboratory, United States

    3 publications · 3.8K citations

    3

    h-index

  5. EB
    Eric Blanc

    Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Germany

    3 publications · 767 citations

    3

    h-index

1–5 of 423

Institutions

117

  1. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    6 h-index

    16 publications

    6.3K citations

  2. University of California, Berkeley

    Berkeley, United States

    5 h-index

    6 publications

    3.9K citations

  3. Los Alamos National Laboratory

    Los Alamos, United States

    4 h-index

    4 publications

    5.8K citations

  4. Goethe University Frankfurt

    Frankfurt am Main, Germany

    4 h-index

    20 publications

    547 citations

  5. University of Oxford

    Oxford, United Kingdom

    4 h-index

    7 publications

    31.2K citations

  6. Lawrence Berkeley National Laboratory

    Berkeley, United States

    4 h-index

    15 publications

    15.1K citations

  7. University of York

    York, United Kingdom

    4 h-index

    5 publications

    30.6K citations

  8. Forschungszentrum Jülich

    Jülich, Germany

    4 h-index

    7 publications

    434 citations

1–8 of 117

Venues

  1. 14

    h-index

  2. 6

    h-index

  3. Acta Crystallographica Section A

    3 publications · 286 citations

    3

    h-index

  4. Journal of Structural Biology

    3 publications · 105 citations

    3

    h-index

  5. 3

    h-index

1–5