Concepedia

Read-across Hypothesis Development

Read-Across Hypothesis Development is the systematic formulation of a scientifically justified assumption that enables the prediction of a target chemical’s property or toxicity by leveraging data from analogous source chemicals, grounded in a defined mechanistic rationale and structural or biological similarity.

11

Publications

814

Citations

64

Authors

26

Institutions

Publications per year

2017–2026

6

Parents

Publications

11

The Read-Across Hypothesis and Environmental Risk Assessment of Pharmaceuticals

Mariann Rand‐Weaver, Luigi Margiotta‐Casaluci, Alpa V. Patel et al. · Environmental Science & Technology · 2013 · 208 citations · Full text

, , +14

A framework for grouping and read-across of nanomaterials- supporting innovation and risk assessment

Vicki Stone, Stefania Gottardo, Eric A.J. Bleeker et al. · Nano Today · 2020 · 151 citations · Full text

, , +17

Quantitative Cross-Species Extrapolation between Humans and Fish: The Case of the Anti-Depressant Fluoxetine

Luigi Margiotta‐Casaluci, Stewart F. Owen, Rob I. Cumming et al. · PLoS ONE · 2014 · 135 citations · Full text

, , +14

Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information

Imran Shah, Jie Liu, Richard Judson et al. · Regulatory Toxicology and Pharmacology · 2016 · 94 citations · Full text

, , +13

Building scientific confidence in the development and evaluation of read-across

Grace Patlewicz, Nicholas Ball, Peter J. Boogaard et al. · Regulatory Toxicology and Pharmacology · 2015 · 68 citations

, , +12

1–5 of 11

Authors

64

  1. GP
    Grace Patlewicz

    Environmental Protection Agency, United States

    3 publications · 190 citations

    3

    h-index

  2. SF
    Stewart F. Owen

    AstraZeneca (United Kingdom), United Kingdom

    3 publications · 373 citations

    3

    h-index

  3. GH
    Grace H. Panter

    AstraZeneca (United Kingdom), United Kingdom

    3 publications · 373 citations

    3

    h-index

  4. MR
    Mariann Rand‐Weaver

    Brunel University of London, United Kingdom

    3 publications · 373 citations

    3

    h-index

  5. LM
    Luigi Margiotta‐Casaluci

    Brunel University of London, United Kingdom

    2 publications · 343 citations

    2

    h-index

1–5 of 64

Institutions

26

  1. Brunel University of London

    London, United Kingdom

    3 h-index

    11 publications

    1.5K citations

  2. AstraZeneca (United Kingdom)

    Cambridge, United Kingdom

    3 h-index

    11 publications

    1.2K citations

  3. Environmental Protection Agency

    Washington, United States

    2 h-index

    12 publications

    666 citations

  4. Dow Chemical (United States)

    Midland, United States

    2 h-index

    3 publications

    154 citations

  5. Brixham Community Hospital

    Brixham, United Kingdom

    2 h-index

    6 publications

    536 citations

  6. Research Triangle Park Foundation

    Durham, United States

    2 h-index

    7 publications

    526 citations

  7. Faculty (United Kingdom)

    London, United Kingdom

    1 h-index

    1 publications

    21 citations

  8. IDEAconsult

    Sofia, Bulgaria

    1 h-index

    1 publications

    151 citations

1–8 of 26

Venues

  1. Regulatory Toxicology and Pharmacology

    RTP · 4 publications · 204 citations

    4

    h-index

  2. Toxicology

    2 publications · 65 citations

    2

    h-index

  3. Chemosphere

    1 publications · 30 citations

    1

    h-index

  4. PLoS ONE

    1 publications · 135 citations

    1

    h-index

  5. Environmental Science Nano

    1 publications · 21 citations

    1

    h-index

1–5