Concepedia

Reactive Intermediate Trapping

Reactive Intermediate Trapping is a specialized experimental methodology in mechanistic toxicology that involves the covalent capture of chemically reactive metabolites by nucleophilic trapping agents to facilitate their detection and structural characterization.

144

Publications

5.6K

Citations

507

Authors

160

Institutions

Publications per year

2017–2026

21

Parents

Publications

144

The Reactivity of Molecules Trapped within the SAPO-34 Cavities in the Methanol-to-Hydrocarbons Reaction

Bjørnar Arstad, Stein Kolboe · Journal of the American Chemical Society · 2001 · 345 citations

, , +6

Clozapine is oxidized by activated human neutrophils to a reactive nitrenium ion that irreversibly binds to the cells.

Zhichao Liu, Jack Uetrecht · Journal of Pharmacology and Experimental Therapeutics · 1995 · 204 citations

, , +11

Kinetics and Mechanism of the Sonolytic Degradation of CCl<sub>4</sub>:  Intermediates and Byproducts

Inez Hua, Michael R. Hoffmann · Environmental Science & Technology · 1996 · 190 citations

, , +13

Direct Synthesis of α-Trifluoromethyl Ketone from (Hetero)arylacetylene: Design, Intermediate Trapping, and Mechanistic Investigations

Arun Maji, Avijit Hazra, Debabrata Maiti · Organic Letters · 2014 · 123 citations

, , +14

Aspects of double-column gas chromatography with glass capillaries involving intermediate trapping

G. Schomburg, H. Husmann, F. Weeke · Journal of Chromatography A · 1975 · 121 citations

, , +11

1–5 of 144

Authors

507

  1. MA
    Mohammad Anary‐Abbasinejad

    Islamic Azad University, Yazd, Iran

    4 publications · 76 citations

    4

    h-index

  2. JU
    Jack Uetrecht

    University of Toronto, Canada

    4 publications · 371 citations

    4

    h-index

  3. RM
    Ross McLellan

    University of Strathclyde, United Kingdom

    3 publications · 92 citations

    3

    h-index

  4. MH
    Mohammad H. Mosslemin

    Islamic Azad University, Yazd, Iran

    3 publications · 55 citations

    3

    h-index

  5. AR
    Alan R. Kennedy

    University of Strathclyde, United Kingdom

    3 publications · 92 citations

    3

    h-index

1–5 of 507

Institutions

160

  1. University of Toronto

    Toronto, Canada

    5 h-index

    5 publications

    209 citations

  2. Islamic Azad University, Yazd

    Yazd, Iran

    4 h-index

    14 publications

    272 citations

  3. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    7 publications

    389 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    9 publications

    425 citations

  5. University of Strathclyde

    Glasgow, United Kingdom

    3 h-index

    12 publications

    400 citations

  6. Diamond Light Source

    Didcot, United Kingdom

    2 h-index

    2 publications

    114 citations

  7. Nagasaki University

    Nagasaki, Japan

    2 h-index

    9 publications

    193 citations

  8. Brookhaven National Laboratory

    Upton, United States

    2 h-index

    2 publications

    76 citations

1–8 of 160

Venues

  1. Journal of the American Chemical Society

    JACS · 25 publications · 1.4K citations

    21

    h-index

  2. The Journal of Organic Chemistry

    JOC · 11 publications · 256 citations

    11

    h-index

  3. Tetrahedron Letters

    8 publications · 210 citations

    8

    h-index

  4. Organic Letters

    OL · 6 publications · 369 citations

    6

    h-index

  5. Drug Metabolism and Disposition

    5 publications · 183 citations

    5

    h-index

1–5