Concepedia

Reaction Essentiality Analysis

Reaction Essentiality Analysis is a computational method in systems biology that identifies the indispensable set of metabolic reactions required for cellular survival under specific environmental and genetic conditions by systematically evaluating the phenotypic impact of reaction knockouts within a metabolic network model.

15

Publications

472

Citations

53

Authors

41

Institutions

Publications per year

2017–2026

3

Parents

Publications

15

Low degree metabolites explain essential reactions and enhance modularity in biological networks

Areejit Samal, Shalini Singh, Varun Giri et al. · BMC Bioinformatics · 2006 · 72 citations · Full text

, , +12

Superessential reactions in metabolic networks

Aditya Barve, João F. Matias Rodrigues, Andreas Wagner · Proceedings of the National Academy of Sciences · 2012 · 65 citations · Full text

, , +13

Spontaneous Reaction Silencing in Metabolic Optimization

Takashi Nishikawa, Natali Gulbahce, Adilson E. Motter · PLoS Computational Biology · 2008 · 48 citations · Full text

, , +14

Machine learning based analyses on metabolic networks supports high-throughput knockout screens

Kitiporn Plaimas, Jan‐Philipp Mallm, Marcus Oswald et al. · BMC Systems Biology · 2008 · 46 citations · Full text

, , +15

Exploiting the pathway structure of metabolism to reveal high-order epistasis

Marcin Imieliński, Călin Belta · BMC Systems Biology · 2008 · 43 citations · Full text

, , +13

1–5 of 15

Authors

53

  1. AW
    Andreas Wagner

    University of Zurich, Switzerland

    2 publications · 90 citations

    2

    h-index

  2. NG
    Nidhi Gupta

    Central University of Rajasthan, India

    1 publications · 15 citations

    1

    h-index

  3. ZN
    Zoran Nikoloski

    Max Planck Institute of Molecular Plant Physiology, Germany

    1 publications · 15 citations

    1

    h-index

  4. RB
    Rui Benfeitas

    Science for Life Laboratory, Sweden

    1 publications · 10 citations

    1

    h-index

  5. GB
    Gholamreza Bidkhori

    Science for Life Laboratory, Sweden

    1 publications · 10 citations

    1

    h-index

1–5 of 53

Institutions

41

  1. Santa Fe Institute

    Santa Fe, United States

    3 h-index

    3 publications

    162 citations

  2. University of Zurich

    Zurich, Switzerland

    2 h-index

    3 publications

    115 citations

  3. SIB Swiss Institute of Bioinformatics

    Lausanne, Switzerland

    2 h-index

    5 publications

    245 citations

  4. Jawaharlal Nehru Centre for Advanced Scientific Research

    Bengaluru, India

    1 h-index

    1 publications

    72 citations

  5. University of Delhi

    New Delhi, India

    1 h-index

    4 publications

    288 citations

  6. Guru Gobind Singh Indraprastha University

    Delhi, India

    1 h-index

    1 publications

    72 citations

  7. KTH Royal Institute of Technology

    Stockholm, Sweden

    1 h-index

    7 publications

    70 citations

  8. Science for Life Laboratory

    Stockholm, Sweden

    1 h-index

    7 publications

    70 citations

1–8 of 41

Venues

  1. BMC Systems Biology

    2 publications · 89 citations

    2

    h-index

  2. Methods in molecular biology

    Book series · 1 publications · 15 citations

    1

    h-index

  3. Scientific Reports

    1 publications · 12 citations

    1

    h-index

  4. Genome biology

    1 publications · 20 citations

    1

    h-index

  5. Metabolites

    1 publications · 12 citations

    1

    h-index

1–5