Concepedia

Rapsyn Function

Rapsyn Function is a molecular scaffolding mechanism that specifically mediates the clustering and stabilization of acetylcholine receptors at the postsynaptic membrane of the neuromuscular junction through its interaction with the receptor complex and the underlying cytoskeleton.

99

Publications

6.3K

Citations

320

Authors

136

Institutions

Publications per year

2017–2026

4

Parents

Publications

99

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice

Medha Gautam, Peter G. Noakes, Jacqueline L. Mudd et al. · Nature · 1995 · 541 citations

, , +16

Rapsyn Is Required for MuSK Signaling and Recruits Synaptic Components to a MuSK-Containing Scaffold

Elizabeth D. Apel, David J. Glass, Lisa M. Moscoso et al. · Neuron · 1997 · 242 citations · Full text

, , +14

Rapsyn Mutations in Humans Cause Endplate Acetylcholine-Receptor Deficiency and Myasthenic Syndrome

Kinji Ohno, Andrew G. Engel, Xin‐Ming Shen et al. · The American Journal of Human Genetics · 2002 · 238 citations · Full text

, , +16

Rapsyn may function as a link between the acetylcholine receptor and the agrin-binding dystrophin-associated glycoprotein complex

Elizabeth D. Apel, Steven L. Roberds, Kevin P. Campbell et al. · Neuron · 1995 · 205 citations · Full text

, , +10

Mechanism of nicotinic acetylcholine receptor cluster formation by rapsyn

Manjunath Ramarao, Jonathan B. Cohen · Proceedings of the National Academy of Sciences · 1998 · 156 citations · Full text

, , +17

1–5 of 99

Authors

320

  1. JP
    John P. Merlie

    Washington University in St. Louis, United States

    7 publications · 1K citations

    7

    h-index

  2. PG
    Peter G. Noakes

    The University of Queensland, Australia

    6 publications · 801 citations

    6

    h-index

  3. MA
    Mohammed Akaaboune

    University of Michigan, United States

    6 publications · 121 citations

    6

    h-index

  4. LM
    Lin Mei

    Augusta University, United States

    6 publications · 548 citations

    6

    h-index

  5. JR
    Joshua R. Sanes

    Harvard University, United States

    6 publications · 1.1K citations

    6

    h-index

1–5 of 320

Institutions

136

  1. Washington University in St. Louis

    St Louis, United States

    11 h-index

    27 publications

    2.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    24 publications

    1.1K citations

  3. University of California, Davis

    Davis, United States

    7 h-index

    29 publications

    1.2K citations

  4. University of Michigan

    Ann Arbor, United States

    6 h-index

    16 publications

    310 citations

  5. Augusta University

    Augusta, United States

    6 h-index

    38 publications

    3.2K citations

  6. Université Paris Cité

    Paris, France

    6 h-index

    25 publications

    1.2K citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    13 publications

    1.2K citations

  8. Sorbonne Université

    Paris, France

    5 h-index

    19 publications

    718 citations

1–8 of 136

Venues

  1. Journal of Neuroscience

    19 publications · 1.2K citations

    18

    h-index

  2. Journal of Biological Chemistry

    JBC · 12 publications · 842 citations

    11

    h-index

  3. Neuron

    7 publications · 880 citations

    7

    h-index

  4. Neuroscience

    6 publications · 178 citations

    6

    h-index

  5. Molecular and Cellular Neuroscience

    MCN · 6 publications · 236 citations

    6

    h-index

1–5