Concepedia

Rab Prenylation

Rab Prenylation is a post-translational modification process in which Rab GTPases are covalently attached to isoprenoid lipid groups, thereby enabling their membrane association and functional regulation within intracellular trafficking pathways.

102

Publications

6.1K

Citations

409

Authors

181

Institutions

Publications per year

2017–2026

9

Parents

Publications

102

Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys.

Miguel C. Seabra, Joseph L. Goldstein, Thomas C. Südhof et al. · Journal of Biological Chemistry · 1992 · 323 citations · Full text

, , +9

Rab escort protein‐1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes.

Kirill Alexandrov, Hisanori Horiuchi, Olivia Steele‐Mortimer et al. · The EMBO Journal · 1994 · 233 citations · Full text

, , +9

Deficient Geranylgeranylation of Ram/Rab27 in Choroideremia

Miguel C. Seabra, Y K Ho, Janmeet Anant · Journal of Biological Chemistry · 1995 · 220 citations · Full text

, , +15

Structure of Rab GDP-Dissociation Inhibitor in Complex with Prenylated YPT1 GTPase

Alexey Rak, Olena Pylypenko, Thomas Durek et al. · Science · 2003 · 213 citations

, , +17

Isoprenoid modification of rab proteins terminating in CC or CXC motifs.

Roya Khosravi‐Far, Robert J. Lutz, Adrienne D. Cox et al. · Proceedings of the National Academy of Sciences · 1991 · 177 citations

, , +14

1–5 of 102

Authors

409

  1. KA
    Kirill Alexandrov

    The University of Queensland, Australia

    20 publications · 1.4K citations

    19

    h-index

  2. RS
    Roger S. Goody

    Max Planck Institute of Molecular Physiology, Germany

    19 publications · 1.2K citations

    18

    h-index

  3. MC
    Miguel C. Seabra

    Imperial College London, United Kingdom

    14 publications · 1.6K citations

    14

    h-index

  4. HW
    Herbert Waldmann

    Max Planck Institute of Molecular Physiology, Germany

    13 publications · 893 citations

    13

    h-index

  5. YW
    Yao‐Wen Wu

    Max Planck Institute of Molecular Physiology, Germany

    10 publications · 504 citations

    10

    h-index

1–5 of 409

Institutions

181

  1. Max Planck Institute of Molecular Physiology

    Dortmund, Germany

    19 h-index

    144 publications

    9.3K citations

  2. Max Planck Society

    Munich, Germany

    11 h-index

    48 publications

    3K citations

  3. Imperial College London

    London, United Kingdom

    6 h-index

    18 publications

    1.6K citations

  4. Harvard University

    Cambridge, United States

    6 h-index

    30 publications

    1.2K citations

  5. The University of Queensland

    Brisbane, Australia

    5 h-index

    8 publications

    388 citations

  6. Scripps Research Institute

    San Diego, United States

    5 h-index

    7 publications

    434 citations

  7. TU Dortmund University

    Dortmund, Germany

    5 h-index

    26 publications

    2.5K citations

  8. Roswell Park Comprehensive Cancer Center

    Buffalo, United States

    4 h-index

    23 publications

    2.2K citations

1–8 of 181

Venues

  1. Journal of Biological Chemistry

    JBC · 27 publications · 1.9K citations

    21

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 693 citations

    6

    h-index

  3. Molecular Biology of the Cell

    MBC · 5 publications · 262 citations

    5

    h-index

  4. Biochemical Journal

    BJ · 5 publications · 128 citations

    5

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 4 publications · 154 citations

    4

    h-index

1–5