Concepedia

Rab Localization Specificity

Rab Localization Specificity is a molecular targeting mechanism that determines the precise subcellular compartmentalization of Rab GTPases through unique combinations of guanine nucleotide exchange factors, GTPase-activating proteins, and effector proteins, thereby ensuring spatial fidelity in membrane trafficking regulation.

40

Publications

2.6K

Citations

202

Authors

86

Institutions

Publications per year

2017–2026

2

Parents

Publications

40

RabGEFs are a major determinant for specific Rab membrane targeting

Julia Blümer, Juliana Sophie Rey, Leif Dehmelt et al. · The Journal of Cell Biology · 2013 · 190 citations · Full text

, , +15

Structure, Exchange Determinants, and Family-Wide Rab Specificity of the Tandem Helical Bundle and Vps9 Domains of Rabex-5

Anna Delprato, Eric Merithew, David G. Lambright · Cell · 2004 · 177 citations · Full text

, , +17

Isoprenoid modification of rab proteins terminating in CC or CXC motifs.

Roya Khosravi‐Far, Robert J. Lutz, Adrienne D. Cox et al. · Proceedings of the National Academy of Sciences · 1991 · 177 citations

, , +14

Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization.

Anne Lütcke, Sanna Jansson, Robert G. Parton et al. · The Journal of Cell Biology · 1993 · 142 citations · Full text

, , +10

Dual Prenylation Is Required for Rab Protein Localization and Function

Monica Calero, Catherine Z. Chen, Nena J. Winand et al. · Molecular Biology of the Cell · 2003 · 136 citations · Full text

, , +15

1–5 of 40

Authors

202

  1. RS
    Roger S. Goody

    Max Planck Institute of Molecular Physiology, Germany

    3 publications · 294 citations

    3

    h-index

  2. MZ
    Marino Zerial

    Max Planck Institute of Molecular Cell Biology and Genetics, Germany

    3 publications · 197 citations

    3

    h-index

  3. AI
    Aymelt Itzen

    Center for Integrated Protein Science Munich, Germany

    3 publications · 294 citations

    3

    h-index

  4. KO
    Kazuhiro Osanai

    Kanazawa Medical University, Japan

    2 publications · 60 citations

    2

    h-index

  5. PC
    Philippe Chavrier

    Institut Curie, France

    2 publications · 180 citations

    2

    h-index

1–5 of 202

Institutions

86

  1. Max Planck Institute of Molecular Physiology

    Dortmund, Germany

    4 h-index

    25 publications

    2.3K citations

  2. Center for Integrated Protein Science Munich

    Munich, Germany

    3 h-index

    3 publications

    294 citations

  3. Imperial College London

    London, United Kingdom

    3 h-index

    10 publications

    654 citations

  4. University of Colorado Denver

    Denver, United States

    2 h-index

    4 publications

    100 citations

  5. Technical University of Munich

    Munich, Germany

    2 h-index

    2 publications

    268 citations

  6. European Molecular Biology Laboratory

    Heidelberg, Germany

    2 h-index

    9 publications

    1.2K citations

  7. Nippon Dental University

    Tokyo, Japan

    2 h-index

    8 publications

    264 citations

  8. Kanazawa Medical University

    Kanazawa, Japan

    2 h-index

    14 publications

    420 citations

1–8 of 86

Venues

  1. The Journal of Cell Biology

    JCB · 3 publications · 430 citations

    3

    h-index

  2. Traffic

    3 publications · 147 citations

    3

    h-index

  3. Nature Communications

    2 publications · 105 citations

    2

    h-index

  4. FEBS Letters

    2 publications · 113 citations

    2

    h-index

  5. Journal of Cell Science

    2 publications · 165 citations

    2

    h-index

1–5