Concepedia

Rab Inactivation

Rab Inactivation is a biochemical regulatory process in which Rab GTPases are converted from their active GTP-bound state to their inactive GDP-bound state through the action of GTPase-activating proteins (GAPs), thereby terminating their function in membrane trafficking.

24

Publications

1.4K

Citations

145

Authors

75

Institutions

Publications per year

2017–2026

6

Parents

Publications

24

A Rab GAP cascade defines the boundary between two Rab GTPases on the secretory pathway

Félix Rivera-Molina, Peter Novick · Proceedings of the National Academy of Sciences · 2009 · 167 citations · Full text

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Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase

Christopher L. Brett, Rachael L. Plemel, Braden T. Lobingier et al. · The Journal of Cell Biology · 2008 · 149 citations · Full text

, , +15

Deregulation of Rab and Rab Effector Genes in Bladder Cancer

Joel R. Ho, Elodie Chapeaublanc, Lisa A. Kirkwood et al. · PLoS ONE · 2012 · 123 citations · Full text

, , +17

Crystal Structures of a Rab Protein in its Inactive and Active Conformations

Christopher Stroupe, Axel T. Brünger · Journal of Molecular Biology · 2000 · 112 citations

, , +16

Rab3 GTPase-activating protein regulates synaptic transmission and plasticity through the inactivation of Rab3

Ayuko Sakane, S Manabe, Hiroyoshi Ishizaki et al. · Proceedings of the National Academy of Sciences · 2006 · 107 citations · Full text

, , +17

1–5 of 24

Authors

145

  1. YT
    Yoshimi Takai

    Kobe University, Japan

    3 publications · 242 citations

    3

    h-index

  2. HK
    Hiroshi Kawabe

    Keio University, Japan

    2 publications · 135 citations

    2

    h-index

  3. MT
    Masakazu Takeuchi

    The University of Osaka, Japan

    2 publications · 135 citations

    2

    h-index

  4. TS
    Takuya Sasaki

    The University of Osaka, Japan

    2 publications · 178 citations

    2

    h-index

  5. YL
    Ying‐Hung Lin

    Fu Jen Catholic University, Taiwan

    2 publications · 55 citations

    2

    h-index

1–5 of 145

Institutions

75

  1. The University of Osaka

    Osaka, Japan

    3 h-index

    14 publications

    974 citations

  2. Yale University

    New Haven, United States

    2 h-index

    3 publications

    307 citations

  3. KAN Research Institute

    Kobe, Japan

    2 h-index

    4 publications

    270 citations

  4. Center for Integrated Protein Science Munich

    Munich, Germany

    2 h-index

    3 publications

    92 citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    3 publications

    373 citations

  6. Tokushima University

    Tokushima, Japan

    2 h-index

    4 publications

    392 citations

  7. National Cheng Kung University

    Tainan City, Taiwan

    2 h-index

    10 publications

    199 citations

  8. Technical University of Munich

    Munich, Germany

    2 h-index

    3 publications

    92 citations

1–8 of 75

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 274 citations

    2

    h-index

  2. PLoS ONE

    2 publications · 189 citations

    2

    h-index

  3. 1

    h-index

  4. International Journal of Andrology

    1 publications · 29 citations

    1

    h-index

  5. Genes to Cells

    1 publications · 64 citations

    1

    h-index

1–5