Concepedia

Rab Activation

Rab Activation is a biochemical regulatory mechanism that functions as a molecular switch governing intracellular membrane trafficking through the GTP-dependent transition of Rab GTPases from an inactive GDP-bound state to an active GTP-bound conformation.

129

Publications

10.6K

Citations

695

Authors

236

Institutions

Publications per year

2017–2026

36

Parents

Publications

129

Evolution of the rab family of small GTP-binding proteins

José B. Pereira‐Leal, Miguel C. Seabra · Journal of Molecular Biology · 2001 · 767 citations

, , +12

Phosphatidylinositol-3-OH kinases are Rab5 effectors

Savvas Christoforidis, Marta Miączyńska, Keith Ashman et al. · Nature Cell Biology · 1999 · 627 citations

, , +10

Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome

Christopher J. Westlake, Lisa M. Baye, Maxence V. Nachury et al. · Proceedings of the National Academy of Sciences · 2011 · 431 citations · Full text

, , +17

Rab27a Is Required for Regulated Secretion in Cytotoxic T Lymphocytes

Jane C. Stinchcombe, Duarte C. Barral, Emilie H. Mules et al. · The Journal of Cell Biology · 2001 · 409 citations

, , +12

The <i>Legionella</i> Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b

Matthias Müller, Heide Peters, Julia Blümer et al. · Science · 2010 · 350 citations

, , +15

1–5 of 129

Authors

695

  1. AI
    Aymelt Itzen

    Center for Integrated Protein Science Munich, Germany

    9 publications · 914 citations

    9

    h-index

  2. MC
    Miguel C. Seabra

    Imperial College London, United Kingdom

    7 publications · 1.4K citations

    7

    h-index

  3. FA
    Francis A. Barr

    University of Oxford, United Kingdom

    6 publications · 769 citations

    6

    h-index

  4. KM
    Karin M. Reinisch

    Yale University, United States

    5 publications · 506 citations

    5

    h-index

  5. PS
    Peter S. McPherson

    Montreal Neurological Institute and Hospital, Canada

    5 publications · 269 citations

    5

    h-index

1–5 of 695

Institutions

236

  1. Stanford University

    Stanford, United States

    8 h-index

    31 publications

    2.5K citations

  2. Technical University of Munich

    Munich, Germany

    8 h-index

    15 publications

    879 citations

  3. Yale University

    New Haven, United States

    8 h-index

    31 publications

    4.2K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    31 publications

    6.7K citations

  5. Center for Integrated Protein Science Munich

    Munich, Germany

    7 h-index

    14 publications

    903 citations

  6. University of Massachusetts Chan Medical School

    Worcester, United States

    6 h-index

    15 publications

    1.7K citations

  7. Max Planck Institute of Molecular Physiology

    Dortmund, Germany

    6 h-index

    38 publications

    4.9K citations

  8. Imperial College London

    London, United Kingdom

    6 h-index

    17 publications

    2.9K citations

1–8 of 236

Venues

  1. The Journal of Cell Biology

    JCB · 9 publications · 1.3K citations

    9

    h-index

  2. Journal of Biological Chemistry

    JBC · 9 publications · 480 citations

    9

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 884 citations

    8

    h-index

  4. Molecular Biology of the Cell

    MBC · 7 publications · 281 citations

    7

    h-index

  5. The EMBO Journal

    6 publications · 529 citations

    6

    h-index

1–5