Concepedia

Concept

pyroptosis

Parents

538

Publications

64.3K

Citations

3.8K

Authors

815

Institutions

About

Pyroptosis is a distinct form of programmed cell death investigated as a key concept in cellular immunology and pathology. This process is characterized by inflammasome activation, caspase-dependent or independent cleavage of gasdermin proteins, rapid plasma membrane pore formation, cell swelling, and lytic release of pro-inflammatory intracellular contents, highlighting its significance in innate host defense and inflammatory diseases.

Top Authors

Rankings shown are based on concept H-Index.

EA

University of North Carolina at Chapel Hill

YZ

Soochow University

SG

Jilin University

FS

National Institute of Biological Sciences, Beijing

TK

St. Jude Children's Research Hospital

Top Institutions

Rankings shown are based on concept H-Index.

Fudan University

Shanghai, China

Sichuan University

Chengdu, China