Concepedia

Purification Behavior

Purification Behavior is a developability assessment criterion that evaluates the feasibility and efficiency of isolating a candidate therapeutic molecule from impurities during downstream processing, distinguishing it from other assessment dimensions by focusing specifically on the physicochemical and operational challenges inherent in the purification stage of biotherapeutic development.

61

Publications

2.9K

Citations

222

Authors

72

Institutions

Publications per year

2017–2026

8

Parents

Publications

61

Production and analysis of special high-purity acids purified by subboiling distillation

Edwin C. Kuehner, Robert Alvarez, Paul J. Paulsen et al. · Analytical Chemistry · 1972 · 279 citations

, , +7

Succinate dehydrogenase. I. Purification, molecular properties, and substructure

Youssef Hatefi, Kenneth Andrew Davis · Biochemistry · 1971 · 253 citations

, , +14

Molecular properties, partial purification, and assay by incubation period measurements of the hamster scrapie agent

Stanley B. Prusiner, Darlene Groth, S. Patricia Cochran et al. · Biochemistry · 1980 · 216 citations

, , +12

Purification of a rat neurotensin receptor expressed in <i>Escherichia coli</i>

Julie A. Tucker, Reinhard Grisshammer · Biochemical Journal · 1996 · 204 citations · Full text

, , +15

Murin histocompatibility-2 (H-2) alloantigens. Purification and some chemical properties of soluble products from H-2<sup>b</sup> and H-2<sup>d</sup> genotypes released by papain digestion of membrane fractions

Akira Shimada, Stanley G. Nathenson · Biochemistry · 1969 · 141 citations

, , +13

1–5 of 61

Authors

222

  1. MM
    Massimo Morbidelli

    ETH Zurich, Switzerland

    2 publications · 150 citations

    2

    h-index

  2. LA
    Luís A. Passarinha

    University of Beira Interior, Portugal

    2 publications · 23 citations

    2

    h-index

  3. MM
    Masakuni Matsuoka

    Tokyo University of Agriculture and Technology, Japan

    2 publications · 36 citations

    2

    h-index

  4. HT
    Hiroshi Takiyama

    Tokyo University of Agriculture and Technology, Japan

    2 publications · 51 citations

    2

    h-index

  5. MJ
    Maria João Bonifácio

    Bial (Portugal), Portugal

    2 publications · 23 citations

    2

    h-index

1–5 of 222

Institutions

72

  1. Tokyo University of Agriculture and Technology

    Tokyo, Japan

    3 h-index

    9 publications

    189 citations

  2. University of Cambridge

    Cambridge, United Kingdom

    2 h-index

    2 publications

    128 citations

  3. Bial (Portugal)

    Porto, Portugal

    2 h-index

    2 publications

    23 citations

  4. ETH Zurich

    Zurich, Switzerland

    2 h-index

    5 publications

    366 citations

  5. University of Beira Interior

    Covilha, Portugal

    2 h-index

    11 publications

    126 citations

  6. Chinese University of Hong Kong

    Hong Kong, Hong Kong

    2 h-index

    3 publications

    65 citations

  7. Nankai University

    Tianjin, China

    1 h-index

    5 publications

    155 citations

  8. Foshan University

    Foshan, China

    1 h-index

    2 publications

    74 citations

1–8 of 72

Venues

  1. Biochemistry

    7 publications · 896 citations

    7

    h-index

  2. Biotechnology and Bioengineering

    4 publications · 225 citations

    4

    h-index

  3. The Journal of Biochemistry

    JB · 3 publications · 80 citations

    3

    h-index

  4. Journal of Separation Science

    3 publications · 36 citations

    3

    h-index

  5. Separation and Purification Technology

    2 publications · 43 citations

    2

    h-index

1–5