Concepedia

Proteoglycan Degradation

Proteoglycan Degradation is a biochemical process involving the enzymatic breakdown of proteoglycans, characterized by the cleavage of glycosidic and peptide bonds within their core protein and glycosaminoglycan chains, primarily mediated by proteases and glycosidases in connective tissue remodeling and pathological conditions.

635

Publications

38.3K

Citations

2.3K

Authors

640

Institutions

Publications per year

2017–2026

35

Parents

Publications

635

The Degradation of Human Endothelial Cell-derived Perlecan and Release of Bound Basic Fibroblast Growth Factor by Stromelysin, Collagenase, Plasmin, and Heparanases

John M. Whitelock, Alan D. Murdoch, Renato V. Iozzo et al. · Journal of Biological Chemistry · 1996 · 589 citations · Full text

, , +15

Isolation and characterization of proteoglycans from the swarm rat chondrosarcoma.

Theodore R. Oegema, Vincent Hascall, Dominic D. Dziewiatkowski · Journal of Biological Chemistry · 1975 · 580 citations · Full text

, , +9

TIMP-3 Is a Potent Inhibitor of Aggrecanase 1 (ADAM-TS4) and Aggrecanase 2 (ADAM-TS5)

Masahide Kashiwagi, Micky D. Tortorella, Hideaki Nagase et al. · Journal of Biological Chemistry · 2001 · 507 citations · Full text

, , +17

Matrix Metalloproteinases And Aggrecanase

Sally Roberts, Bruce Caterson, J. Menage et al. · Spine · 2000 · 504 citations

, , +17

Degradation of decorin by matrix metalloproteinases: identification of the cleavage sites, kinetic analyses and transforming growth factor-<i>β</i>1 release

Kazushi Imai, Ari HIRAMATSU, Daikichi Fukushima et al. · Biochemical Journal · 1997 · 439 citations · Full text

, , +17

1–5 of 635

Authors

2.3K

  1. PJ
    Peter J. Roughley

    Shriners Hospitals for Children - Canada, Canada

    36 publications · 3.1K citations

    30

    h-index

  2. JS
    John S. Mort

    McGill University, Canada

    22 publications · 2K citations

    21

    h-index

  3. BC
    Bruce Caterson

    Cardiff University, United Kingdom

    14 publications · 1.5K citations

    14

    h-index

  4. CH
    Clare Hughes

    Cardiff University, United Kingdom

    12 publications · 1.1K citations

    12

    h-index

  5. HK
    Hans Kresse

    University of Münster, Germany

    9 publications · 341 citations

    9

    h-index

1–5 of 2.3K

Institutions

640

  1. McGill University

    Montreal, Canada

    23 h-index

    87 publications

    6.5K citations

  2. Lund University

    Lund, Sweden

    22 h-index

    72 publications

    3.6K citations

  3. Rush University Medical Center

    Chicago, United States

    21 h-index

    94 publications

    5.1K citations

  4. Shriners Hospitals for Children - Canada

    Montreal, Canada

    18 h-index

    47 publications

    2.6K citations

  5. Tissue Genetics (United States)

    Aurora, United States

    16 h-index

    37 publications

    2.6K citations

  6. Montreal Children's Hospital

    Montreal, Canada

    11 h-index

    26 publications

    2.8K citations

  7. Cardiff University

    Cardiff, United Kingdom

    11 h-index

    41 publications

    2.8K citations

  8. Radboud University Nijmegen

    Nijmegen, The Netherlands

    10 h-index

    34 publications

    1.9K citations

1–8 of 640

Venues

  1. Biochemical Journal

    BJ · 76 publications · 5.2K citations

    41

    h-index

  2. Journal of Biological Chemistry

    JBC · 61 publications · 5.6K citations

    40

    h-index

  3. PubMed

    Repository · 51 publications · 2.2K citations

    29

    h-index

  4. Arthritis & Rheumatism

    36 publications · 3.3K citations

    28

    h-index

  5. Journal of Orthopaedic Research®

    18 publications · 834 citations

    17

    h-index

1–5