Concepedia

Protein-protein Interface Stabilization

Protein-Protein Interface Stabilization is a methodological framework in structural bioengineering that enhances the thermodynamic stability and specificity of interacting protein surfaces through targeted amino acid modifications or non-covalent interactions at the interfacial region.

70

Publications

4.3K

Citations

366

Authors

133

Institutions

Publications per year

2017–2026

27

Parents

Publications

70

Studies of protein‐protein interfaces: A statistical analysis of the hydrophobic effect

Chung‐Jung Tsai, Shuo Liang Lin, Haim J. Wolfson et al. · Protein Science · 1997 · 428 citations · Full text

, , +17

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

Amanda J. Price, Adam J. Fletcher, Torsten Schaller et al. · PLoS Pathogens · 2012 · 272 citations · Full text

, , +17

Conservation and relative importance of residues across protein-protein interfaces

Mainak Guharoy, Pinak Chakrabarti · Proceedings of the National Academy of Sciences · 2005 · 262 citations

, , +17

Embedded cholesterol in the nicotinic acetylcholine receptor

Grace Brannigan, Jérôme Hénin, Richard Law et al. · Proceedings of the National Academy of Sciences · 2008 · 164 citations · Full text

, , +17

Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins

Sebastian Pechmann, Emmanuel D. Levy, Gian Gaetano Tartaglia et al. · Proceedings of the National Academy of Sciences · 2009 · 164 citations · Full text

, , +17

1–5 of 70

Authors

366

  1. CO
    Christian Ottmann

    Eindhoven University of Technology, Netherlands

    7 publications · 257 citations

    7

    h-index

  2. LB
    Luc Brunsveld

    Eindhoven University of Technology, Netherlands

    6 publications · 195 citations

    6

    h-index

  3. JM
    Joris M. C. Adriaans

    Eindhoven University of Technology, Netherlands

    3 publications · 94 citations

    3

    h-index

  4. MB
    Maria Bartel

    Eindhoven University of Technology, Netherlands

    3 publications · 138 citations

    3

    h-index

  5. PJ
    Peter J. Cossar

    Eindhoven University of Technology, Netherlands

    2 publications · 77 citations

    2

    h-index

1–5 of 366

Institutions

133

  1. Eindhoven University of Technology

    Eindhoven, The Netherlands

    7 h-index

    39 publications

    1.3K citations

  2. University of Duisburg-Essen

    Essen, Germany

    5 h-index

    6 publications

    277 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    11 publications

    407 citations

  4. New York University

    New York, United States

    4 h-index

    9 publications

    440 citations

  5. Medical Research Council

    London, United Kingdom

    3 h-index

    16 publications

    2.8K citations

  6. Harvard University

    Cambridge, United States

    3 h-index

    17 publications

    685 citations

  7. Frederick National Laboratory for Cancer Research

    Frederick, United States

    2 h-index

    4 publications

    1.4K citations

  8. Nanyang Technological University

    Singapore, Singapore

    2 h-index

    4 publications

    101 citations

1–8 of 133

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 862 citations

    6

    h-index

  2. Journal of Biological Chemistry

    JBC · 5 publications · 258 citations

    5

    h-index

  3. Protein Science

    PS · 3 publications · 518 citations

    3

    h-index

  4. Biochemistry

    3 publications · 188 citations

    3

    h-index

  5. Journal of the American Chemical Society

    JACS · 3 publications · 78 citations

    3

    h-index

1–5