Adam J. Fletcher

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

Torsten Schaller, Karen E. Ocwieja, Jane Rasaiyaah et al. · PLoS Pathogens · 2011 · 476 citations · Full text

Virus Structure, Replication Efficiency, Viral Replication +14

HIV-1 evades innate immune recognition through specific cofactor recruitment

Jane Rasaiyaah, Choon Ping Tan, Adam J. Fletcher et al. · Nature · 2013 · 450 citations · Full text

Human Retrovirus, Immunology, Antiviral Response +6

Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly

Amanda J. Price, David A. Jacques, William A. McEwan et al. · PLoS Pathogens · 2014 · 298 citations · Full text

Host Cofactors, Protein Assembly, Immunology +18

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

Amanda J. Price, Adam J. Fletcher, Torsten Schaller et al. · PLoS Pathogens · 2012 · 268 citations · Full text

Virus Structure, Viral Replication, Signal Transduction +14

Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21

Adam J. Fletcher, Donna L. Mallery, Ruth Watkinson et al. · Proceedings of the National Academy of Sciences · 2015 · 123 citations · Full text

Tripartite Motif, Immunology, Signal Recognition +18