Concepedia

Protein-protein Interface Modeling

Protein-Protein Interface Modeling is a computational method that specifically predicts the structural and physicochemical characteristics of the contact region formed between two interacting proteins, distinguishing it from broader protein docking approaches by focusing exclusively on the interface geometry, residue contacts, and binding affinity determinants.

176

Publications

14.7K

Citations

696

Authors

333

Institutions

Publications per year

2017–2026

38

Parents

Publications

176

Improved prediction of protein-protein interactions using AlphaFold2

Patrick Bryant, Gabriele Pozzati, Arne Elofsson · Nature Communications · 2022 · 1K citations · Full text

, , +17

Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology

Martino Bertoni, Florian Kiefer, Marco Biasini et al. · Scientific Reports · 2017 · 927 citations · Full text

, , +17

A simple physical model for binding energy hot spots in protein–protein complexes

Tanja Kortemme, David Baker · Proceedings of the National Academy of Sciences · 2002 · 826 citations

, , +17

Contacts-based prediction of binding affinity in protein–protein complexes

Anna Vangone, Alexandre M. J. J. Bonvin · eLife · 2015 · 670 citations · Full text

, , +15

Dissecting protein–protein recognition sites

Pinak Chakrabarti, Joël Janin · Proteins Structure Function and Bioinformatics · 2002 · 577 citations

, , +15

1–5 of 176

Authors

696

  1. RN
    Ruth Nussinov

    Tel Aviv University, Israel

    8 publications · 617 citations

    8

    h-index

  2. JF
    Juan Fernández‐Recio

    Universitat Politècnica de Catalunya, Spain

    7 publications · 571 citations

    7

    h-index

  3. MZ
    Martin Zacharias

    Technical University of Munich, Germany

    6 publications · 410 citations

    6

    h-index

  4. HJ
    Haim J. Wolfson

    Tel Aviv University, Israel

    5 publications · 398 citations

    5

    h-index

  5. JJ
    Jeffrey J. Gray

    Johns Hopkins University, United States

    5 publications · 637 citations

    5

    h-index

1–5 of 696

Institutions

333

  1. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    41 publications

    2.7K citations

  2. Tel Aviv University

    Tel Aviv, Israel

    10 h-index

    22 publications

    1.8K citations

  3. Barcelona Supercomputing Center

    Barcelona, Spain

    7 h-index

    25 publications

    1.3K citations

  4. Universitat Politècnica de Catalunya

    Barcelona, Spain

    7 h-index

    25 publications

    1.3K citations

  5. University of Kansas

    Lawrence, United States

    5 h-index

    12 publications

    538 citations

  6. Johns Hopkins University

    Baltimore, United States

    5 h-index

    19 publications

    2.9K citations

  7. Science Applications International Corporation (United States)

    McLean, United States

    5 h-index

    5 publications

    381 citations

  8. Utrecht University

    Utrecht, The Netherlands

    5 h-index

    15 publications

    2.3K citations

1–8 of 333

Venues

  1. Proteins Structure Function and Bioinformatics

    37 publications · 3K citations

    24

    h-index

  2. Journal of Molecular Biology

    JMB · 13 publications · 1.6K citations

    13

    h-index

  3. PLoS ONE

    11 publications · 719 citations

    10

    h-index

  4. Bioinformatics

    9 publications · 652 citations

    9

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 1.7K citations

    8

    h-index

1–5