Concepedia

Protein Splicing

Protein Splicing is a post-translational modification process in which an internal segment of a polypeptide chain, known as an intein, excises itself and concurrently ligates the flanking sequences, termed exteins, through a peptide bond, resulting in a mature and functionally active protein.

887

Publications

63.6K

Citations

4.5K

Authors

1.3K

Institutions

Publications per year

2017–2026

159

Parents

Publications

887

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

Julie Hollien, Jonathan H. Lin, Han Li et al. · The Journal of Cell Biology · 2009 · 1K citations · Full text

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Function of alternative splicing

Olga Kelemen, Paolo Convertini, Zhaiyi Zhang et al. · Gene · 2012 · 759 citations

, , +9

Dissecting the human BDNF locus: Bidirectional transcription, complex splicing, and multiple promoters

Priit Pruunsild, Anna Kazantseva, Tamara Aid et al. · Genomics · 2007 · 700 citations · Full text

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Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene.

Alberto R. Kornblihtt, Kazuo Umezawa, Karen Vibe‐Pedersen et al. · The EMBO Journal · 1985 · 664 citations · Full text

, , +9

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

Xinping Yang, Jasmin Coulombe‐Huntington, Shuli Kang et al. · Cell · 2016 · 612 citations · Full text

, , +9

1–5 of 887

Authors

4.5K

  1. MX
    Ming‐Qun Xu

    New England Biolabs (United States), United States

    25 publications · 4.2K citations

    25

    h-index

  2. TW
    Tom W. Muir

    Rockefeller University, United States

    28 publications · 3K citations

    25

    h-index

  3. HD
    Henning D. Mootz

    University of Münster, Germany

    23 publications · 1.5K citations

    20

    h-index

  4. FB
    Francine B. Perler

    New England Biolabs (United States), United States

    24 publications · 3.8K citations

    19

    h-index

  5. HP
    Henry Paulus

    Harvard University, United States

    18 publications · 1.9K citations

    17

    h-index

1–5 of 4.5K

Institutions

1.3K

  1. New England Biolabs (United States)

    Ipswich, United States

    36 h-index

    151 publications

    23.8K citations

  2. Harvard University

    Cambridge, United States

    22 h-index

    106 publications

    20.7K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    21 h-index

    54 publications

    11.5K citations

  4. Inserm

    Paris, France

    18 h-index

    117 publications

    5K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    18 h-index

    83 publications

    4.5K citations

  6. The University of Tokyo

    Tokyo, Japan

    18 h-index

    69 publications

    5.4K citations

  7. Rockefeller University

    New York, United States

    16 h-index

    44 publications

    4.5K citations

  8. Boston Biomedical Research Institute

    Watertown, United States

    16 h-index

    35 publications

    3.1K citations

1–8 of 1.3K

Venues

  1. Journal of Biological Chemistry

    JBC · 91 publications · 6.4K citations

    52

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 39 publications · 4.4K citations

    33

    h-index

  3. Nucleic Acids Research

    33 publications · 3.3K citations

    25

    h-index

  4. PLoS ONE

    23 publications · 1.3K citations

    17

    h-index

  5. Journal of the American Chemical Society

    JACS · 16 publications · 1.5K citations

    16

    h-index

1–5