Concepedia

Protein Multivalency

Protein Multivalency is a biochemical phenomenon in which a single protein molecule simultaneously engages multiple binding sites or interaction partners through structurally distinct, often modular, domains or motifs, thereby enhancing binding avidity, specificity, or signal integration beyond what is achievable through monovalent interactions.

21

Publications

1.8K

Citations

86

Authors

37

Institutions

Publications per year

2017–2026

6

Parents

Publications

21

Multivalency as a Chemical Organization and Action Principle

Carlo Fasting, Christoph A. Schalley, Marcus Weber et al. · Angewandte Chemie International Edition · 2012 · 992 citations

, , +16

Multivalent Antimicrobial Peptides as Therapeutics: Design Principles and Structural Diversities

S. P. Liu, Lei Zhou, Rajamani Lakshminarayanan et al. · International Journal of Peptide Research and Therapeutics · 2010 · 120 citations · Full text

, , +17

Multivalent Carbohydrate Recognition on a Glycodendrimer‐Functionalized Flow‐Through Chip

Hilbert M. Branderhorst, Rob Ruijtenbeek, Rob M. J. Liskamp et al. · ChemBioChem · 2008 · 89 citations

, , +17

Highly-Efficient Purification of Native Polyhistidine-Tagged Proteins by Multivalent NTA-Modified Magnetic Nanoparticles

C. Alexander Valencia, Rihe Liu, Wenbin Lin · Bioconjugate Chemistry · 2007 · 69 citations · Full text

, , +17

Protein Nanotube Selectively Cleavable with DNA: Supramolecular Polymerization of “DNA-Appended Molecular Chaperones”

Daiki Kashiwagi, Seunghyun Sim, Tatsuya Niwa et al. · Journal of the American Chemical Society · 2017 · 65 citations

, , +17

1–5 of 21

Authors

86

  1. EK
    Ernst‐Walter Knapp

    Freie Universität Berlin, Germany

    2 publications · 1K citations

    2

    h-index

  2. JD
    Jens Dernedde

    Charité - Universitätsmedizin Berlin, Germany

    2 publications · 1K citations

    2

    h-index

  3. RH
    Rainer Haag

    Freie Universität Berlin, Germany

    2 publications · 1K citations

    2

    h-index

  4. FR
    F.J. Reithel

    University of Oregon, United States

    2 publications · 101 citations

    2

    h-index

  5. IC
    Ilias Christodoulopoulos

    University of Southern California, United States

    1 publications · 32 citations

    1

    h-index

1–5 of 86

Institutions

37

  1. Freie Universität Berlin

    Berlin, Germany

    3 h-index

    11 publications

    6.1K citations

  2. University of Oregon

    Eugene, United States

    2 h-index

    4 publications

    202 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    3 publications

    121 citations

  4. Tokyo Institute of Technology

    Tokyo, Japan

    2 h-index

    6 publications

    198 citations

  5. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    2 h-index

    3 publications

    1K citations

  6. Université de Lille

    Lille, France

    1 h-index

    1 publications

    19 citations

  7. Massachusetts General Hospital

    Boston, United States

    1 h-index

    1 publications

    24 citations

  8. Scuola Internazionale Superiore di Studi Avanzati

    Trieste, Italy

    1 h-index

    1 publications

    51 citations

1–8 of 37

Venues

  1. Biochemical Society Transactions

    1 publications · 12 citations

    1

    h-index

  2. The Plant Cell

    1 publications · 19 citations

    1

    h-index

  3. Archives of Biochemistry and Biophysics

    ABB · 1 publications · 43 citations

    1

    h-index

  4. Journal of Biological Chemistry

    JBC · 1 publications · 58 citations

    1

    h-index

  5. Contrast Media & Molecular Imaging

    CMMI · 1 publications · 12 citations

    1

    h-index

1–5