Concepedia

Protein Interface Energetics

Protein Interface Energetics is a computational and biophysical framework that quantifies the energetic contributions of intermolecular interactions at the interface of protein-protein complexes to predict and analyze binding affinity and specificity.

300

Publications

20.4K

Citations

1K

Authors

422

Institutions

Publications per year

2017–2026

70

Parents

Publications

300

A simple physical model for binding energy hot spots in protein–protein complexes

Tanja Kortemme, David Baker · Proceedings of the National Academy of Sciences · 2002 · 826 citations

, , +17

Contacts-based prediction of binding affinity in protein–protein complexes

Anna Vangone, Alexandre M. J. J. Bonvin · eLife · 2015 · 670 citations · Full text

, , +15

Computational Alanine Scanning of Protein-Protein Interfaces

Tanja Kortemme, David E. Kim, David Baker · Science s STKE · 2004 · 612 citations

, , +16

Protein–protein interactions: Structurally conserved residues distinguish between binding sites and exposed protein surfaces

Buyong Ma, Tal Elkayam, Haim J. Wolfson et al. · Proceedings of the National Academy of Sciences · 2003 · 604 citations · Full text

, , +15

Energetics of protein-protein interactions: Analysis ofthe Barnase-Barstar interface by single mutations and double mutant cycles

Gideon Schreiber, Alan R. Fersht · Journal of Molecular Biology · 1995 · 573 citations

, , +15

1–5 of 300

Authors

1K

  1. MJ
    Maria J. Ramos

    Universidade do Porto, Portugal

    9 publications · 511 citations

    9

    h-index

  2. PA
    Pedro Alexandrino Fernandes

    Universidade do Porto, Portugal

    8 publications · 492 citations

    8

    h-index

  3. IS
    Irina S. Moreira

    Universidade do Porto, Portugal

    7 publications · 466 citations

    7

    h-index

  4. DB
    David Baker

    University of Washington, United States

    6 publications · 1.7K citations

    6

    h-index

  5. ÖK
    Özlem Keskin

    Koç University, Türkiye

    6 publications · 673 citations

    6

    h-index

1–5 of 1K

Institutions

422

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    20 publications

    5.1K citations

  2. Universidade do Porto

    Porto, Portugal

    10 h-index

    32 publications

    1.7K citations

  3. University of Washington

    Seattle, United States

    8 h-index

    23 publications

    4.4K citations

  4. Rede de Química e Tecnologia

    Porto, Portugal

    7 h-index

    23 publications

    1.5K citations

  5. Nanyang Technological University

    Singapore, Singapore

    7 h-index

    16 publications

    620 citations

  6. University of Chicago

    Chicago, United States

    6 h-index

    26 publications

    2.1K citations

  7. Universitat Politècnica de Catalunya

    Barcelona, Spain

    6 h-index

    13 publications

    1.3K citations

  8. Utrecht University

    Utrecht, The Netherlands

    6 h-index

    16 publications

    1.8K citations

1–8 of 422

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 19 publications · 3.2K citations

    18

    h-index

  2. Proteins Structure Function and Bioinformatics

    26 publications · 1.7K citations

    18

    h-index

  3. Biochemistry

    14 publications · 652 citations

    14

    h-index

  4. Protein Science

    PS · 14 publications · 1.2K citations

    14

    h-index

  5. The Journal of Physical Chemistry B

    19 publications · 521 citations

    14

    h-index

1–5