Concepedia

Protein Complex Evolution

Protein Complex Evolution is a theoretical framework that characterizes the evolutionary mechanisms and constraints governing the assembly, architecture, and functional adaptation of multi-protein complexes across species through the divergence and conservation of protein-protein interaction interfaces and subunit composition.

56

Publications

3.5K

Citations

239

Authors

142

Institutions

Publications per year

2017–2026

15

Parents

Publications

56

Assembly reflects evolution of protein complexes

Emmanuel D. Levy, Elisabetta Boeri Erba, Carol V. Robinson et al. · Nature · 2008 · 431 citations · Full text

, , +12

Evolutionary conservation of components of the protein translocation complex

Enno Hartmann, Thomas Sommer, Siegfried Prehn et al. · Nature · 1994 · 289 citations

, , +8

Sm and Sm‐like proteins assemble in two related complexes of deep evolutionary origin

Josefa Salgado, Elisabeth Bragado‐Nilsson, Stefanie Kandels‐Lewis et al. · The EMBO Journal · 1999 · 262 citations · Full text

, , +12

Protein Complexes Are under Evolutionary Selection to Assemble via Ordered Pathways

Joseph A. Marsh, Helena Hernández, Zoe Hall et al. · Cell · 2013 · 257 citations · Full text

, , +17

Evolution of protein complexes by duplication of homomeric interactions

José B. Pereira‐Leal, Emmanuel D. Levy, Christel Kamp et al. · Genome biology · 2007 · 199 citations · Full text

, , +17

1–5 of 56

Authors

239

  1. SA
    Sarah A. Teichmann

    Wellcome Sanger Institute, United Kingdom

    6 publications · 1.1K citations

    6

    h-index

  2. JA
    Joseph A. Marsh

    University of Edinburgh, United Kingdom

    5 publications · 531 citations

    5

    h-index

  3. SE
    Sebastian E. Ahnert

    University of Cambridge, United Kingdom

    3 publications · 403 citations

    3

    h-index

  4. ‎S
    ‎Berend Snel

    Utrecht University, Netherlands

    3 publications · 98 citations

    3

    h-index

  5. RG
    Raphaël Guérois

    Commissariat à l'Énergie Atomique et aux Énergies Alternatives, France

    3 publications · 145 citations

    3

    h-index

1–5 of 239

Institutions

142

  1. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    12 publications

    505 citations

  2. European Bioinformatics Institute

    Cambridge, United Kingdom

    5 h-index

    10 publications

    1.6K citations

  3. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    5 h-index

    15 publications

    2.4K citations

  4. Wellcome Sanger Institute

    Cambridge, United Kingdom

    4 h-index

    5 publications

    467 citations

  5. University of Cambridge

    Cambridge, United Kingdom

    4 h-index

    5 publications

    1.1K citations

  6. Tel Aviv University

    Tel Aviv, Israel

    4 h-index

    10 publications

    411 citations

  7. Commissariat à l'Énergie Atomique et aux Énergies Alternatives

    Paris, France

    3 h-index

    8 publications

    386 citations

  8. Institute of Genetics and Cancer

    Edinburgh, United Kingdom

    3 h-index

    4 publications

    248 citations

1–8 of 142

Venues

  1. PLoS Computational Biology

    7 publications · 245 citations

    7

    h-index

  2. Nucleic Acids Research

    3 publications · 95 citations

    3

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 136 citations

    3

    h-index

  4. BMC Genomics

    2 publications · 51 citations

    2

    h-index

  5. eLife

    2 publications · 127 citations

    2

    h-index

1–5