Concepedia

Protein Aggregation Kinetics

Protein Aggregation Kinetics is the biophysical framework that characterizes the time-dependent rates and molecular mechanisms governing the assembly of misfolded proteins into ordered aggregates, distinguishing it from static structural analyses by focusing on the dynamic progression of aggregation processes.

1.4K

Publications

85.8K

Citations

4.7K

Authors

1.3K

Institutions

Publications per year

2017–2026

348

Parents

Publications

1.4K

Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates

Vasco Filipe, Andrea Hawe, Wim Jiskoot · Pharmaceutical Research · 2010 · 1.8K citations · Full text

, , +17

An Analytical Solution to the Kinetics of Breakable Filament Assembly

Tuomas P. J. Knowles, Christopher A. Waudby, Glyn L. Devlin et al. · Science · 2009 · 1.1K citations

, , +17

Rationalization of the effects of mutations on peptide andprotein aggregation rates

Fabrizio Chiti, Massimo Stefani, Niccolò Taddei et al. · Nature · 2003 · 1.1K citations

, , +12

The Hydrodynamic Radii of Macromolecules and Their Effect on Red Blood Cell Aggregation

Jonathan K. Armstrong, R.B. Wenby, Herbert J. Meiselman et al. · Biophysical Journal · 2004 · 829 citations · Full text

, , +16

Quantitative mass imaging of single biological macromolecules

Gavin Young, Nikolas Hundt, Daniel Cole et al. · Science · 2018 · 821 citations · Full text

, , +17

1–5 of 1.4K

Authors

4.7K

  1. TP
    Tuomas P. J. Knowles

    University of Cambridge, United Kingdom

    36 publications · 4.6K citations

    28

    h-index

  2. CM
    Christopher M. Dobson

    University of Cambridge, United Kingdom

    28 publications · 6.1K citations

    25

    h-index

  3. CJ
    Christopher J. Roberts

    University of Delaware, United States

    25 publications · 2.2K citations

    23

    h-index

  4. MV
    Michele Vendruscolo

    University of Cambridge, United Kingdom

    20 publications · 3.1K citations

    17

    h-index

  5. GM
    Georg Meisl

    University of Cambridge, United Kingdom

    20 publications · 2.3K citations

    17

    h-index

1–5 of 4.7K

Institutions

1.3K

  1. University of Cambridge

    Cambridge, United Kingdom

    48 h-index

    374 publications

    42.7K citations

  2. University of Delaware

    Newark, United States

    27 h-index

    80 publications

    5.7K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    23 h-index

    84 publications

    4.2K citations

  4. Amgen (United States)

    Thousand Oaks, United States

    23 h-index

    114 publications

    16.8K citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    19 h-index

    54 publications

    6.3K citations

  6. Lund University

    Lund, Sweden

    19 h-index

    71 publications

    6.7K citations

  7. Harvard University

    Cambridge, United States

    18 h-index

    41 publications

    4.2K citations

  8. University College London

    London, United Kingdom

    18 h-index

    50 publications

    2.4K citations

1–8 of 1.3K

Venues

  1. Biochemistry

    66 publications · 4.7K citations

    39

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 43 publications · 6.1K citations

    35

    h-index

  3. Biophysical Journal

    57 publications · 4.8K citations

    34

    h-index

  4. The Journal of Physical Chemistry B

    58 publications · 2.9K citations

    30

    h-index

  5. Journal of Biological Chemistry

    JBC · 37 publications · 3.5K citations

    29

    h-index

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