Protease Therapy

Protease Therapy is a therapeutic method that employs proteolytic enzymes to selectively degrade pathological proteins or modulate disease-related proteolytic processes in the treatment of medical conditions.

203

Publications

20.1K

Citations

1.1K

Authors

405

Institutions

Publications per year

2017–2026

Parents

Therapeutic Enzymes

Publications

203

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

David D. Ho, Avidan U. Neumann, Alan S. Perelson et al. · Nature · 1995 · 4.3K citations

Life Sciences, Immunology, Infectious Diseases +14

HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time

Alan S. Perelson, Avidan U. Neumann, Martin Markowitz et al. · Science · 1996 · 3.5K citations

Life Sciences, Infectious Diseases, Microbiology +16

A Short-Term Study of the Safety, Pharmacokinetics, and Efficacy of Ritonavir, an Inhibitor of HIV-1 Protease

Sven A. Danner, Andrew Carr, John M. Leonard et al. · New England Journal of Medicine · 1995 · 573 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Effect of Combination Therapy Including Protease Inhibitors on Mortality among Children and Adolescents Infected with HIV-1

Steven L. Gortmaker, Michael D. Hughes, Joseph S. Cervia et al. · New England Journal of Medicine · 2001 · 502 citations · Full text

Medicine, Infectious Diseases, Pediatrics +17

A Preliminary Study of Ritonavir, an Inhibitor of HIV-1 Protease, to Treat HIV-1 Infection

Martin Markowitz, Michael S. Saag, William G. Powderly et al. · New England Journal of Medicine · 1995 · 492 citations · Full text

Pharmacy, Infectious Diseases, Pharmacotherapy +17

1–5 of 203

Authors

1.1K

AM
Amanda Mocroft
University College London, United Kingdom
6 publications · 915 citations
6
h-index
JM
John M. Leonard
Abbott Fund, United States
6 publications · 9K citations
6
h-index
GC
Geneviève Chêne
Inserm, France
5 publications · 370 citations
5
h-index
DD
David D. Ho
Aaron Diamond AIDS Research Center, United States
5 publications · 8.4K citations
5
h-index
AS
Alan S. Perelson
Los Alamos National Laboratory, United States
4 publications · 7.9K citations
4
h-index

1–5 of 1.1K

Institutions

405

1–8 of 405

Venues

PubMed
Repository · 23 publications · 482 citations
15
h-index
Antimicrobial Agents and Chemotherapy
AAC · 10 publications · 585 citations
10
h-index
JAIDS Journal of Acquired Immune Deficiency Syndromes
9 publications · 595 citations
9
h-index
AIDS
7 publications · 682 citations
7
h-index
Journal of Virology
JVI · 6 publications · 828 citations
6
h-index

1–5