Concepedia

Protease Imbalance

Protease Imbalance is a pathophysiological condition characterized by an aberrant ratio of proteolytic enzymes to their endogenous inhibitors in chronic wounds, leading to excessive degradation of extracellular matrix components and impaired tissue repair.

73

Publications

5.2K

Citations

444

Authors

157

Institutions

Publications per year

2017–2026

7

Parents

Publications

73

Cystatin C deficiency in human atherosclerosis and aortic aneurysms

Guo-Ping Shi, Galina K. Sukhova, Anders Grubb et al. · Journal of Clinical Investigation · 1999 · 448 citations · Full text

, , +15

Antielastases of the human alveolar structures. Implications for the protease-antiprotease theory of emphysema.

James E. Gadek, G A Fells, R L Zimmerman et al. · Journal of Clinical Investigation · 1981 · 434 citations · Full text

, , +14

Effect of High Dose Inhaled Steroid on Cells, Cytokines, and Proteases in Induced Sputum in Chronic Obstructive Pulmonary Disease

Sarah V. Culpitt, Wasim Maziak, Stelios Loukidis et al. · American Journal of Respiratory and Critical Care Medicine · 1999 · 419 citations

, , +17

Protease-Antiprotease Imbalance in the Lungs of Children with Cystic Fibrosis

P. Birrer, Noel G. McElvaney, A Rüdeberg et al. · American Journal of Respiratory and Critical Care Medicine · 1994 · 381 citations

, , +16

Nrf2‐deficient mice are highly susceptible to cigarette smoke‐induced emphysema

Takashi Iizuka, Yukio Ishii, Ken Itoh et al. · Genes to Cells · 2005 · 333 citations

, , +17

1–5 of 73

Authors

444

  1. GL
    Gordon L. Snider

    Boston University, United States

    2 publications · 132 citations

    2

    h-index

  2. DJ
    Donald J. Cannon

    Boston Biomedical Research Institute, United States

    2 publications · 225 citations

    2

    h-index

  3. SJ
    Sabina Janciauskiene

    Lund University, Sweden

    2 publications · 42 citations

    2

    h-index

  4. RG
    Ronald G. Crystal

    Cornell University, United States

    2 publications · 815 citations

    2

    h-index

  5. OE
    Oliver Eickelberg

    Helmholtz Zentrum München, Germany

    2 publications · 79 citations

    2

    h-index

1–5 of 444

Institutions

157

  1. University of British Columbia

    Vancouver, Canada

    3 h-index

    15 publications

    1.7K citations

  2. Imperial College London

    London, United Kingdom

    3 h-index

    16 publications

    3.1K citations

  3. University of Bonn

    Bonn, Germany

    2 h-index

    9 publications

    492 citations

  4. Helsinki University Hospital

    Helsinki, Finland

    2 h-index

    6 publications

    244 citations

  5. Ludwig-Maximilians-Universität München

    Munich, Germany

    2 h-index

    8 publications

    316 citations

  6. Inserm

    Paris, France

    2 h-index

    18 publications

    1.2K citations

  7. University of Helsinki

    Helsinki, Finland

    2 h-index

    9 publications

    289 citations

  8. German Center for Lung Research

    Giessen, Germany

    2 h-index

    8 publications

    316 citations

1–8 of 157

Venues

  1. PubMed

    Repository · 13 publications · 668 citations

    13

    h-index

  2. American Journal of Respiratory and Critical Care Medicine

    AJRCCM · 5 publications · 949 citations

    5

    h-index

  3. Scientific Reports

    2 publications · 84 citations

    2

    h-index

  4. Thorax

    2 publications · 77 citations

    2

    h-index

  5. Journal of Clinical Investigation

    JCI · 2 publications · 882 citations

    2

    h-index

1–5