Concepedia

Protease Imaging

Protease Imaging is a molecular imaging technique that specifically visualizes the activity, localization, and dynamics of proteolytic enzymes in biological systems through the use of targeted probes or reporters designed to undergo protease-dependent activation or cleavage.

93

Publications

6.4K

Citations

469

Authors

174

Institutions

Publications per year

2017–2026

26

Parents

Publications

93

Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes

Galia Blum, Georges von Degenfeld, Milton Merchant et al. · Nature Chemical Biology · 2007 · 464 citations

, , +16

Dynamic imaging of protease activity with fluorescently quenched activity-based probes

Galia Blum, Stefanie Mullins, Kinneret Keren et al. · Nature Chemical Biology · 2005 · 359 citations

, , +16

A Near‐Infrared‐Fluorescence‐Quenched Gold‐Nanoparticle Imaging Probe for In Vivo Drug Screening and Protease Activity Determination

Seulki Lee, Eui‐Joon Cha, Kyeongsoon Park et al. · Angewandte Chemie International Edition · 2008 · 348 citations

, , +17

Graphene Oxide–Peptide Conjugate as an Intracellular Protease Sensor for Caspase‐3 Activation Imaging in Live Cells

Hai‐Bo Wang, Qing Zhang, Xia Chu et al. · Angewandte Chemie International Edition · 2011 · 326 citations

, , +15

Near-infrared optical imaging of proteases in cancer.

Umar Mahmood, Ralph Weissleder · PubMed · 2003 · 279 citations

, , +17

1–5 of 93

Authors

469

  1. RW
    Ralph Weissleder

    Massachusetts General Hospital, United States

    10 publications · 1.3K citations

    10

    h-index

  2. MB
    Matthew Bogyo

    Stanford University, United States

    6 publications · 1K citations

    6

    h-index

  3. UM
    Umar Mahmood

    Massachusetts General Hospital, United States

    5 publications · 604 citations

    5

    h-index

  4. CS
    Charles S. Craik

    University of California, San Francisco, United States

    4 publications · 150 citations

    4

    h-index

  5. GB
    Galia Blum

    Hebrew University of Jerusalem, Israel

    4 publications · 884 citations

    4

    h-index

1–5 of 469

Institutions

174

  1. Massachusetts General Hospital

    Boston, United States

    12 h-index

    57 publications

    5K citations

  2. Stanford University

    Stanford, United States

    11 h-index

    44 publications

    6.2K citations

  3. Harvard University

    Cambridge, United States

    7 h-index

    34 publications

    5.1K citations

  4. University of California, San Francisco

    San Francisco, United States

    5 h-index

    18 publications

    883 citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    29 publications

    1.5K citations

  6. Chinese Academy of Sciences

    Beijing, China

    3 h-index

    12 publications

    304 citations

  7. CytomX Therapeutics (United States)

    South San Francisco, United States

    3 h-index

    12 publications

    372 citations

  8. University of California San Diego

    San Diego, United States

    3 h-index

    25 publications

    811 citations

1–8 of 174

Venues

  1. Angewandte Chemie International Edition

    7 publications · 1.1K citations

    7

    h-index

  2. Chemical Communications

    ChemComm · 6 publications · 186 citations

    6

    h-index

  3. Angewandte Chemie

    6 publications · 246 citations

    6

    h-index

  4. Journal of the American Chemical Society

    JACS · 4 publications · 580 citations

    4

    h-index

  5. Cancer Research

    3 publications · 128 citations

    3

    h-index

1–5