Concepedia

Property-based Library Design

Property-Based Library Design is a chemical library design strategy that systematically selects or generates compound collections based on predefined molecular properties to optimize desired biological or physicochemical characteristics.

21

Publications

957

Citations

127

Authors

44

Institutions

Publications per year

2017–2026

6

Parents

Publications

21

Combinatorial Library Design Using a Multiobjective Genetic Algorithm

Valerie J. Gillet, Wael Khatib, Peter Willett et al. · Journal of Chemical Information and Computer Sciences · 2002 · 152 citations

, , +14

Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein–Protein Interactions with Heat Shock Protein 70 (Hsp70)

Hao Shao, Xiaokai Li, Michael A. Moses et al. · Journal of Medicinal Chemistry · 2018 · 120 citations · Full text

, , +14

Property-Based Design of GPCR-Targeted Library

Konstantin V. Balakin, Sergey E. Tkachenko, Stanley A. Lang et al. · Journal of Chemical Information and Computer Sciences · 2002 · 72 citations

, , +17

Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening

Christopher R. Wellaway, Dominique Amans, Paul Bamborough et al. · Journal of Medicinal Chemistry · 2020 · 71 citations · Full text

, , +14

Assessment of chemical libraries for their druggability

Suzanne Sirois, George Hatzakis, Dong‐Qing Wei et al. · Computational Biology and Chemistry · 2005 · 68 citations

, , +12

1–5 of 21

Authors

127

  1. LS
    Liming Shu

    The University of Tokyo, Japan

    1 publications · 52 citations

    1

    h-index

  2. VV
    Vladímir V. Kouznetsov

    Industrial University of Santander, Colombia

    1 publications · 12 citations

    1

    h-index

  3. GH
    George Hatzakis

    Montreal General Hospital, Canada

    1 publications · 68 citations

    1

    h-index

  4. CB
    Christophe Buyck

    Janssen (Belgium), Belgium

    1 publications · 39 citations

    1

    h-index

  5. BH
    Byron Hann

    University of California, San Francisco, United States

    1 publications · 120 citations

    1

    h-index

1–5 of 127

Institutions

44

  1. Simulations Plus (United States)

    Lancaster, United States

    1 h-index

    3 publications

    204 citations

  2. Laboratoire d’immunologie intégrative du cancer

    Paris, France

    1 h-index

    1 publications

    52 citations

  3. Secretaría Nacional de Ciencia, Tecnología e Innovación

    Panama City, Panama

    1 h-index

    1 publications

    16 citations

  4. Jones Institute

    Carlsbad, United States

    1 h-index

    1 publications

    39 citations

  5. Johnson & Johnson (United States)

    New Brunswick, United States

    1 h-index

    7 publications

    273 citations

  6. Tianjin Normal University

    Tianjin, China

    1 h-index

    3 publications

    204 citations

  7. Lawrence Berkeley National Laboratory

    Berkeley, United States

    1 h-index

    4 publications

    152 citations

  8. Pfizer (United States)

    New York, United States

    1 h-index

    3 publications

    105 citations

1–8 of 44

Venues

  1. 4

    h-index

  2. Journal of Medicinal Chemistry

    2 publications · 191 citations

    2

    h-index

  3. Journal of Chemical Information and Modeling

    JCIM · 2 publications · 74 citations

    2

    h-index

  4. PubMed

    Repository · 1 publications · 21 citations

    1

    h-index

  5. ChemInform

    1 publications · 38 citations

    1

    h-index

1–5