Concepedia

Profilin Function

Profilin Function is a molecular regulatory mechanism in cytoskeletal dynamics that governs actin polymerization by sequestering actin monomers and facilitating their nucleotide exchange, thereby controlling the availability and assembly competence of actin subunits at sites of cytoskeletal remodeling.

357

Publications

28.8K

Citations

1.6K

Authors

513

Institutions

Publications per year

2017–2026

54

Parents

Publications

357

Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cells

Lars Carlsson, Lina Nyström, Ingegerd C. Sundkvist et al. · Journal of Molecular Biology · 1977 · 700 citations

, , +16

Profilins constitute a novel family of functional plant pan-allergens.

Rudolf Valenta, Michael Duchêne, C. Ebner et al. · The Journal of Experimental Medicine · 1992 · 634 citations · Full text

, , +12

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

Chi-Hong Wu, Claudia Fallini, Nicola Ticozzi et al. · Nature · 2012 · 599 citations

, , +12

How profilin promotes actin filament assembly in the presence of thymosin β4

Dominique Pantaloni, Marie‐France Carlier · Cell · 1993 · 535 citations

, , +14

The proline‐rich focal adhesion and microfilament protein VASP is a ligand for profilins.

Matthias Reinhard, Klaudia Giehl, Kathrin Abel et al. · The EMBO Journal · 1995 · 480 citations · Full text

, , +14

1–5 of 357

Authors

1.6K

  1. UL
    Uno Lindberg

    Stockholm University, Sweden

    18 publications · 1.9K citations

    17

    h-index

  2. TD
    Thomas D. Pollard

    Yale University, United States

    19 publications · 2.3K citations

    17

    h-index

  3. CJ
    Christopher J. Staiger

    Purdue University West Lafayette, United States

    13 publications · 1.4K citations

    13

    h-index

  4. PR
    Partha Roy

    University of Pittsburgh, United States

    12 publications · 795 citations

    12

    h-index

  5. RK
    Roger Karlsson

    Stockholm University, Sweden

    11 publications · 495 citations

    11

    h-index

1–5 of 1.6K

Institutions

513

  1. Stockholm University

    Stockholm, Sweden

    21 h-index

    74 publications

    4.1K citations

  2. Johns Hopkins University

    Baltimore, United States

    18 h-index

    66 publications

    7.7K citations

  3. Purdue University West Lafayette

    West Lafayette, United States

    15 h-index

    35 publications

    3.1K citations

  4. Johns Hopkins Medicine

    Baltimore, United States

    12 h-index

    45 publications

    6.2K citations

  5. University of Pittsburgh

    Pittsburgh, United States

    11 h-index

    42 publications

    2.7K citations

  6. University of Bonn

    Bonn, Germany

    11 h-index

    23 publications

    2.7K citations

  7. University of Vienna

    Vienna, Austria

    11 h-index

    48 publications

    9K citations

  8. Harvard University

    Cambridge, United States

    11 h-index

    24 publications

    1.3K citations

1–8 of 513

Venues

  1. Journal of Biological Chemistry

    JBC · 35 publications · 2.6K citations

    25

    h-index

  2. The Journal of Cell Biology

    JCB · 16 publications · 2.5K citations

    16

    h-index

  3. FEBS Letters

    16 publications · 814 citations

    16

    h-index

  4. Biochemistry

    15 publications · 1.6K citations

    14

    h-index

  5. Molecular Biology of the Cell

    MBC · 11 publications · 1.1K citations

    11

    h-index

1–5