Concepedia

Probe Sensitivity Optimization

Probe Sensitivity Optimization is a methodological framework within molecular probe development that systematically enhances the detection threshold and signal-to-noise ratio of molecular probes to achieve maximal responsiveness to target analytes.

81

Publications

6K

Citations

467

Authors

148

Institutions

Publications per year

2017–2026

20

Parents

Publications

81

Gradient-Tailored Water Suppression for 1H-15N HSQC Experiments Optimized to Retain Full Sensitivity

Vladimı́r Sklenář, Martial Piotto, R. Leppik et al. · Journal of Magnetic Resonance Series A · 1993 · 1.2K citations

, , +4

Analytical sensitivity and efficiency comparisons of SARS-CoV-2 RT–qPCR primer–probe sets

Chantal B. F. Vogels, Anderson F. Brito, Anne L. Wyllie et al. · Nature Microbiology · 2020 · 919 citations · Full text

, , +6

Optimization Strategies for DNA Microarray-Based Detection of Bacteria with 16S rRNA-Targeting Oligonucleotide Probes

Jörg Peplies, Frank Oliver Glöckner, Rudolf Amann · Applied and Environmental Microbiology · 2003 · 197 citations · Full text

, , +13

Advancing NMR Sensitivity for LC-NMR-MS Using a Cryoflow Probe:  Application to the Analysis of Acetaminophen Metabolites in Urine

Manfred Spraul, Amy Freund, R. Nast et al. · Analytical Chemistry · 2003 · 190 citations

, , +15

An Optimized Method for In Situ Hybridization with Signal Amplification That Allows the Detection of Rare mRNAs

Hui Yang, Ina B. Wanner, Stephen D. Roper et al. · Journal of Histochemistry & Cytochemistry · 1999 · 181 citations · Full text

, , +13

1–5 of 81

Authors

467

  1. RW
    R.S. Withers

    Massachusetts Institute of Technology, United States

    2 publications · 358 citations

    2

    h-index

  2. AS
    Arthur S. Edison

    University of Florida, United States

    2 publications · 47 citations

    2

    h-index

  3. LZ
    Li Zhang

    Chongqing Medical University, China

    2 publications · 65 citations

    2

    h-index

  4. JH
    Jeffrey Hoorfar

    Technical University of Denmark, Denmark

    2 publications · 162 citations

    2

    h-index

  5. MH
    Mathilde H. Josefsen

    Technical University of Denmark, Denmark

    2 publications · 162 citations

    2

    h-index

1–5 of 467

Institutions

148

  1. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    18 publications

    5.7K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    11 publications

    1.4K citations

  3. University of Illinois Urbana-Champaign

    Urbana, United States

    3 h-index

    6 publications

    204 citations

  4. Tsinghua University

    Beijing, China

    2 h-index

    10 publications

    832 citations

  5. University of California, Berkeley

    Berkeley, United States

    2 h-index

    11 publications

    767 citations

  6. Bruker (United States)

    Billerica, United States

    2 h-index

    10 publications

    1.8K citations

  7. East China University of Science and Technology

    Shanghai, China

    2 h-index

    11 publications

    397 citations

  8. Lawrence Berkeley National Laboratory

    Berkeley, United States

    2 h-index

    11 publications

    767 citations

1–8 of 148

Venues

  1. Analytical Chemistry

    6 publications · 456 citations

    6

    h-index

  2. Journal of Virological Methods

    4 publications · 97 citations

    4

    h-index

  3. Journal of Magnetic Resonance Series A

    4 publications · 1.2K citations

    4

    h-index

  4. Journal of the American Chemical Society

    JACS · 4 publications · 470 citations

    4

    h-index

  5. Sensors and Actuators B Chemical

    3 publications · 46 citations

    3

    h-index

1–5