Concepedia

Prion-like Spreading

Prion-Like Spreading is a pathological mechanism in protein aggregation disorders characterized by the self-templated propagation of misfolded proteins between cells or anatomical regions, analogous to prion transmission, thereby driving the progressive dissemination of proteinopathy throughout the nervous system.

114

Publications

10.3K

Citations

880

Authors

309

Institutions

Publications per year

2017–2026

85

Parents

Publications

114

Prion-like spreading of pathological α-synuclein in brain

Masami Masuda‐Suzukake, Takashi Nonaka, Masato Hosokawa et al. · Brain · 2013 · 888 citations · Full text

, , +17

Brain-first versus body-first Parkinson’s disease: a multimodal imaging case-control study

Jacob Horsager, Katrine B. Andersen, Karoline Knudsen et al. · Brain · 2020 · 757 citations

, , +17

Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes

Jinar Rostami, Staffan Holmqvist, Veronica Lindström et al. · Journal of Neuroscience · 2017 · 341 citations · Full text

, , +17

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

Meryem Tardivel, Séverine Bégard, Luc Bousset et al. · Acta Neuropathologica Communications · 2016 · 297 citations · Full text

, , +17

Prion-like disorders: blurring the divide between transmissibility and infectivity

Mimi Cushman, Brian S. Johnson, Oliver D. King et al. · Journal of Cell Science · 2010 · 279 citations

, , +17

1–5 of 114

Authors

880

  1. MH
    Masato Hasegawa

    Tokyo Metropolitan Institute of Medical Science, Japan

    11 publications · 1.9K citations

    11

    h-index

  2. TN
    Takashi Nonaka

    Tokyo Metropolitan Institute of Medical Science, Japan

    7 publications · 1.4K citations

    7

    h-index

  3. RM
    Ronald Melki

    Centre National de la Recherche Scientifique, France

    7 publications · 766 citations

    7

    h-index

  4. MM
    Masami Masuda‐Suzukake

    Tokyo Metropolitan Institute of Medical Science, Japan

    6 publications · 1.4K citations

    6

    h-index

  5. LB
    Luc Bousset

    Centre National de la Recherche Scientifique, France

    5 publications · 696 citations

    5

    h-index

1–5 of 880

Institutions

309

  1. Tokyo Metropolitan Institute of Medical Science

    Tokyo, Japan

    11 h-index

    56 publications

    10.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    27 publications

    2K citations

  3. German Center for Neurodegenerative Diseases

    Bonn, Germany

    8 h-index

    36 publications

    3.1K citations

  4. University of Florida

    Gainesville, United States

    7 h-index

    41 publications

    2.7K citations

  5. Stanford University

    Stanford, United States

    7 h-index

    35 publications

    1.5K citations

  6. University of Pennsylvania

    Philadelphia, United States

    5 h-index

    15 publications

    1.3K citations

  7. University of Oxford

    Oxford, United Kingdom

    5 h-index

    5 publications

    410 citations

  8. Inserm

    Paris, France

    5 h-index

    31 publications

    3.2K citations

1–8 of 309

Venues

  1. Acta Neuropathologica Communications

    15 publications · 1.4K citations

    14

    h-index

  2. Brain

    9 publications · 2.5K citations

    9

    h-index

  3. Scientific Reports

    7 publications · 457 citations

    7

    h-index

  4. Acta Neuropathologica

    7 publications · 725 citations

    7

    h-index

  5. Journal of Biological Chemistry

    JBC · 6 publications · 299 citations

    6

    h-index

1–5