Concepedia

Prion Strain Stability

Prion Strain Stability is a theoretical construct in prion biology that denotes the phenotypic persistence of distinct prion conformations during replication and transmission, distinguishing it from transient or unstable prion variants by its capacity to maintain consistent biological and pathological characteristics across generations.

41

Publications

4.6K

Citations

182

Authors

82

Institutions

Publications per year

2017–2026

6

Parents

Publications

41

A yeast prion provides a mechanism for genetic variation and phenotypic diversity

Heather L. True, Susan Lindquist · Nature · 2000 · 687 citations

, , +16

The physical basis of how prion conformations determine strain phenotypes

Motomasa Tanaka, Sean R. Collins, Brandon H. Toyama et al. · Nature · 2006 · 597 citations

, , +16

Structural insights into a yeast prion illuminate nucleation and strain diversity

Rajaraman Krishnan, Susan Lindquist · Nature · 2005 · 473 citations · Full text

, , +16

Genetic and Environmental Factors Affecting the <i>de novo</i> Appearance of the <i>[PSI</i> + <i>]</i> Prion in <i>Saccharomyces cerevisiae</i>

Irina L. Derkatch, Michael E. Bradley, Ping‐Kun Zhou et al. · Genetics · 1997 · 457 citations · Full text

, , +16

Molecular Basis of a Yeast Prion Species Barrier

Alex Santoso, Peter Chien, Lev Osherovich et al. · Cell · 2000 · 275 citations · Full text

, , +13

1–5 of 41

Authors

182

  1. SB
    Stanley B. Prusiner

    University of California, San Francisco, United States

    5 publications · 544 citations

    5

    h-index

  2. AO
    Abby Oehler

    University of California, San Francisco, United States

    3 publications · 217 citations

    3

    h-index

  3. HL
    Heather L. True

    Washington University in St. Louis, United States

    3 publications · 759 citations

    3

    h-index

  4. KG
    Kurt Giles

    University of California, San Francisco, United States

    3 publications · 353 citations

    3

    h-index

  5. YO
    Yury O. Chernoff

    Georgia Institute of Technology, United States

    3 publications · 596 citations

    3

    h-index

1–5 of 182

Institutions

82

  1. University of California, San Francisco

    San Francisco, United States

    7 h-index

    33 publications

    5.9K citations

  2. Institute for Neurodegenerative Disorders

    New Haven, United States

    5 h-index

    24 publications

    2.2K citations

  3. University of Illinois Chicago

    Chicago, United States

    3 h-index

    8 publications

    2.2K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    7 publications

    3.9K citations

  5. Georgia Institute of Technology

    Atlanta, United States

    3 h-index

    8 publications

    935 citations

  6. Istituto Superiore di Sanità

    Rome, Italy

    3 h-index

    13 publications

    376 citations

  7. Scripps (United States)

    Cincinnati, United States

    2 h-index

    5 publications

    169 citations

  8. Imperial College London

    London, United Kingdom

    2 h-index

    4 publications

    382 citations

1–8 of 82

Venues

  1. PLoS Pathogens

    4 publications · 262 citations

    4

    h-index

  2. Genetics

    3 publications · 607 citations

    3

    h-index

  3. Journal of Molecular Biology

    JMB · 3 publications · 163 citations

    3

    h-index

  4. Journal of Biological Chemistry

    JBC · 3 publications · 221 citations

    3

    h-index

  5. Nature

    3 publications · 1.8K citations

    3

    h-index

1–5