Concepedia

Prion Strain Evolution

Prion Strain Evolution is a theoretical framework that accounts for the heritable variation and selection of prion conformations over time, distinguishing itself from other prion dynamics models by emphasizing the role of structural plasticity and environmental pressures in driving strain-specific adaptation and diversification.

8

Publications

756

Citations

80

Authors

31

Institutions

Publications per year

2017–2026

5

Parents

Publications

8

A Change in the Conformation of Prions Accompanies the Emergence of a New Prion Strain

David Peretz, R. Anthony Williamson, Giuseppe Legname et al. · Neuron · 2002 · 229 citations · Full text

, , +13

A Bovine Prion Acquires an Epidemic Bovine Spongiform Encephalopathy Strain-Like Phenotype on Interspecies Transmission

Vincent Béringue, O. Andreoletti, Annick Le Dur et al. · Journal of Neuroscience · 2007 · 140 citations · Full text

, , +14

A structural basis for prion strain diversity

Szymon W. Manka, Adam Wenborn, Jemma Betts et al. · Nature Chemical Biology · 2023 · 90 citations · Full text

, , +17

Adaptive selection of a prion strain conformer corresponding to established North American CWD during propagation of novel emergent Norwegian strains in mice expressing elk or deer prion protein

Jifeng Bian, Sehun Kim, Sarah J. Kane et al. · PLoS Pathogens · 2021 · 86 citations · Full text

, , +16

The Evolution of Transmissible Prions: The Role of Deformed Templating

Natallia Makarava, Ilia V. Baskakov · PLoS Pathogens · 2013 · 75 citations · Full text

, , +12

1–5 of 8

Authors

80

  1. VB
    Vincent Béringue

    Virologie et Immunologie Moléculaires, France

    3 publications · 259 citations

    3

    h-index

  2. FR
    Fabienne Reine

    Virologie et Immunologie Moléculaires, France

    2 publications · 199 citations

    2

    h-index

  3. AL
    Annick Le Dur

    Virologie et Immunologie Moléculaires, France

    2 publications · 199 citations

    2

    h-index

  4. SJ
    Susan Joiner

    University College London, United Kingdom

    2 publications · 107 citations

    2

    h-index

  5. SW
    Szymon W. Manka

    Institute of Structural and Molecular Biology, United Kingdom

    2 publications · 107 citations

    2

    h-index

1–5 of 80

Institutions

31

  1. Virologie et Immunologie Moléculaires

    Jouy-en-Josas, France

    3 h-index

    16 publications

    1.4K citations

  2. Institute of Structural and Molecular Biology

    London, United Kingdom

    2 h-index

    2 publications

    107 citations

  3. Birkbeck, University of London

    London, United Kingdom

    2 h-index

    2 publications

    107 citations

  4. MRC Prion Unit

    London, United Kingdom

    2 h-index

    12 publications

    642 citations

  5. University College London

    London, United Kingdom

    2 h-index

    12 publications

    642 citations

  6. Centro de Investigación en Sanidad Animal

    Valdeolmos, Spain

    1 h-index

    3 publications

    180 citations

  7. Istituto Superiore di Sanità

    Rome, Italy

    1 h-index

    1 publications

    86 citations

  8. Institute for Neurodegenerative Disorders

    New Haven, United States

    1 h-index

    7 publications

    1.6K citations

1–8 of 31

Venues

  1. PLoS Pathogens

    2 publications · 161 citations

    2

    h-index

  2. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 1 publications · 17 citations

    1

    h-index

  3. Nature Communications

    1 publications · 59 citations

    1

    h-index

  4. Journal of Neuroscience

    1 publications · 140 citations

    1

    h-index

  5. mBio

    1 publications · 60 citations

    1

    h-index

1–5