Concepedia

Primary Microrna Processing

Primary MicroRNA Processing is a molecular biology mechanism that specifically encompasses the initial nuclear cleavage of long primary microRNA transcripts into shorter precursor microRNAs by the microprocessor complex, thereby distinguishing it from subsequent cytoplasmic steps in the microRNA biogenesis pathway.

154

Publications

31.8K

Citations

863

Authors

304

Institutions

Publications per year

2017–2026

49

Parents

Publications

154

miRBase: annotating high confidence microRNAs using deep sequencing data

Ana Kozomara, Sam Griffiths‐Jones · Nucleic Acids Research · 2013 · 5.2K citations · Full text

, , +17

Processing of primary microRNAs by the Microprocessor complex

Ahmet M. Denli, Bastiaan B.J. Tops, Ronald H.A. Plasterk et al. · Nature · 2004 · 2.7K citations

, , +10

MicroRNA maturation: stepwise processing and subcellular localization

Yoontae Lee, Kipyoung Jeon, Jun‐Tae Lee et al. · The EMBO Journal · 2002 · 2.4K citations · Full text

, , +13

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

Xuezhong Cai, Curt H. Hagedorn, Bryan R. Cullen · RNA · 2004 · 1.8K citations · Full text

, , +17

Molecular Basis for the Recognition of Primary microRNAs by the Drosha-DGCR8 Complex

Jinju Han, Yoontae Lee, Kyu‐Hyeon Yeom et al. · Cell · 2006 · 1.5K citations · Full text

, , +13

1–5 of 154

Authors

863

  1. TD
    Trung Duc Nguyen

    Hong Kong University of Science and Technology, Hong Kong SAR China

    7 publications · 272 citations

    6

    h-index

  2. TA
    Tuan Anh Nguyen

    Hong Kong University of Science and Technology, Hong Kong SAR China

    8 publications · 404 citations

    6

    h-index

  3. BR
    Bryan R. Cullen

    Duke Medical Center, United States

    5 publications · 3.5K citations

    5

    h-index

  4. EC
    Eric C. Lai

    Kettering University, United States

    4 publications · 528 citations

    4

    h-index

  5. GR
    Guodong Ren

    Fudan University, China

    4 publications · 273 citations

    4

    h-index

1–5 of 863

Institutions

304

  1. Seoul National University

    Seoul, South Korea

    10 h-index

    40 publications

    25.5K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    23 publications

    5.4K citations

  3. Hong Kong University of Science and Technology

    Hong Kong, Hong Kong

    7 h-index

    33 publications

    1.3K citations

  4. Fudan University

    Shanghai, China

    6 h-index

    26 publications

    3.6K citations

  5. The University of Texas Southwestern Medical Center

    Dallas, United States

    5 h-index

    24 publications

    1.9K citations

  6. University of Hong Kong

    Pok Fu Lam, Hong Kong

    5 h-index

    26 publications

    1K citations

  7. Yale University

    New Haven, United States

    5 h-index

    21 publications

    3.1K citations

  8. Duke Medical Center

    Durham, United States

    5 h-index

    10 publications

    5.7K citations

1–8 of 304

Venues

  1. Nucleic Acids Research

    14 publications · 6.7K citations

    14

    h-index

  2. RNA

    13 publications · 3.4K citations

    13

    h-index

  3. Molecular Cell

    12 publications · 1.4K citations

    12

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 974 citations

    11

    h-index

  5. PLoS ONE

    5 publications · 335 citations

    5

    h-index

1–5