Concepedia

Primary Cilium Function

Primary Cilium Function is a biological process denoting the role of the primary cilium as a specialized signaling organelle that transduces extracellular signals, particularly in the Hedgehog pathway, by spatially compartmentalizing pathway components to regulate graded and context-dependent cellular responses.

676

Publications

54.9K

Citations

3.9K

Authors

1K

Institutions

Publications per year

2017–2026

269

Parents

Publications

676

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

Surya M. Nauli, Francis J. Alenghat, Ying Luo et al. · Nature Genetics · 2003 · 2K citations

, , +14

Vertebrate Smoothened functions at the primary cilium

Kevin C. Corbit, Pia Aanstad, Veena Singla et al. · Nature · 2005 · 1.5K citations

, , +6

Patched1 Regulates Hedgehog Signaling at the Primary Cilium

Rajat Rohatgi, Ljiljana Milenković, Matthew P. Scott · Science · 2007 · 1.5K citations

, , +17

The Polycystic Kidney Disease Proteins, Polycystin-1, Polycystin-2, Polaris, and Cystin, Are Co-Localized in Renal Cilia

Bradley K. Yoder, Xiaoying Hou, Lisa M. Guay‐Woodford · Journal of the American Society of Nephrology · 2002 · 939 citations

, , +16

The Graded Response to Sonic Hedgehog Depends on Cilia Architecture

Tamara Caspary, Christine E. Larkins, Kathryn V. Anderson · Developmental Cell · 2007 · 756 citations · Full text

, , +5

1–5 of 676

Authors

3.9K

  1. ST
    Søren T. Christensen

    University of Copenhagen, Denmark

    15 publications · 1.9K citations

    15

    h-index

  2. CR
    Christopher R. Jacobs

    Stanford University, United States

    11 publications · 957 citations

    11

    h-index

  3. TS
    Tim Stearns

    Stanford University, United States

    11 publications · 927 citations

    11

    h-index

  4. JF
    Jeremy F. Reiter

    University of California, San Francisco, United States

    10 publications · 2.5K citations

    10

    h-index

  5. LB
    Lotte B. Pedersen

    University of Copenhagen, Denmark

    10 publications · 760 citations

    10

    h-index

1–5 of 3.9K

Institutions

1K

  1. Inserm

    Paris, France

    31 h-index

    258 publications

    19.4K citations

  2. Stanford University

    Stanford, United States

    31 h-index

    135 publications

    19K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    31 h-index

    217 publications

    15.1K citations

  4. Harvard University

    Cambridge, United States

    25 h-index

    93 publications

    29.8K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    24 h-index

    75 publications

    18.8K citations

  6. University of California, San Francisco

    San Francisco, United States

    22 h-index

    67 publications

    13.5K citations

  7. Université Paris Cité

    Paris, France

    18 h-index

    105 publications

    7.3K citations

  8. National Institutes of Health

    Bethesda, United States

    17 h-index

    35 publications

    2.8K citations

1–8 of 1K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 27 publications · 3.9K citations

    25

    h-index

  2. The Journal of Cell Biology

    JCB · 24 publications · 2.3K citations

    24

    h-index

  3. Journal of Cell Science

    32 publications · 1.7K citations

    23

    h-index

  4. Molecular Biology of the Cell

    MBC · 26 publications · 1.8K citations

    22

    h-index

  5. PLoS ONE

    24 publications · 1.4K citations

    20

    h-index

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