Concepedia

Pri-microrna Processing

Pri-MicroRNA Processing is the nuclear cleavage event in microRNA biogenesis wherein the microprocessor complex, consisting of Drosha and DGCR8, selectively recognizes and cleaves primary microRNA transcripts (pri-miRNAs) to liberate stem-loop precursor microRNAs, thereby initiating the maturation pathway distinct from cytoplasmic RNA interference mechanisms.

220

Publications

30.2K

Citations

1.3K

Authors

453

Institutions

Publications per year

2017–2026

85

Parents

Publications

220

The Drosha-DGCR8 complex in primary microRNA processing

Jinju Han, Yoontae Lee, Kyu-Hyun Yeom et al. · Genes & Development · 2004 · 2.2K citations · Full text

, , +17

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

Thimmaiah P. Chendrimada, Richard I. Gregory, Easwari Kumaraswamy et al. · Nature · 2005 · 2.1K citations · Full text

, , +14

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

Xuezhong Cai, Curt H. Hagedorn, Bryan R. Cullen · RNA · 2004 · 1.8K citations · Full text

, , +17

Intronic microRNA precursors that bypass Drosha processing

J. Graham Ruby, Calvin H. Jan, David P. Bartel · Nature · 2007 · 1.6K citations · Full text

, , +13

Molecular Basis for the Recognition of Primary microRNAs by the Drosha-DGCR8 Complex

Jinju Han, Yoontae Lee, Kyu‐Hyeon Yeom et al. · Cell · 2006 · 1.5K citations · Full text

, , +13

1–5 of 220

Authors

1.3K

  1. BY
    Bin Yu

    University of Nebraska–Lincoln, United States

    9 publications · 883 citations

    9

    h-index

  2. TD
    Trung Duc Nguyen

    Hong Kong University of Science and Technology, Hong Kong SAR China

    9 publications · 320 citations

    8

    h-index

  3. TA
    Tuan Anh Nguyen

    Hong Kong University of Science and Technology, Hong Kong SAR China

    11 publications · 464 citations

    8

    h-index

  4. FG
    Feng Guo

    University of California, Los Angeles, United States

    7 publications · 454 citations

    7

    h-index

  5. ZS
    Zofia Szweykowska-Kulińska

    Adam Mickiewicz University in Poznań, Poland

    7 publications · 689 citations

    7

    h-index

1–5 of 1.3K

Institutions

453

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    13 h-index

    36 publications

    11.2K citations

  2. Seoul National University

    Seoul, South Korea

    12 h-index

    67 publications

    33.7K citations

  3. Chinese Academy of Sciences

    Beijing, China

    10 h-index

    37 publications

    2.2K citations

  4. Hong Kong University of Science and Technology

    Hong Kong, Hong Kong

    9 h-index

    42 publications

    1.5K citations

  5. University of Hong Kong

    Pok Fu Lam, Hong Kong

    8 h-index

    36 publications

    1.3K citations

  6. University of Nebraska–Lincoln

    Lincoln, United States

    8 h-index

    35 publications

    2K citations

  7. Adam Mickiewicz University in Poznań

    Poznan, Poland

    8 h-index

    48 publications

    4.7K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    27 publications

    1.5K citations

1–8 of 453

Venues

  1. Nucleic Acids Research

    28 publications · 2.1K citations

    25

    h-index

  2. RNA

    17 publications · 4K citations

    16

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 14 publications · 1.7K citations

    14

    h-index

  4. PLoS ONE

    12 publications · 404 citations

    12

    h-index

  5. Molecular Cell

    11 publications · 1.3K citations

    11

    h-index

1–5