Concepedia

Presequence-dependent Import Pathway

The "Presequence-Dependent Import Pathway" is a mitochondrial protein import mechanism that directs nuclear-encoded precursor proteins to the mitochondrial matrix via an N-terminal targeting signal, known as a presequence, which is recognized by receptors of the translocase of the outer membrane (TOM) complex and subsequently translocated through the TIM23 complex in a membrane potential-dependent manner.

80

Publications

6.7K

Citations

329

Authors

102

Institutions

Publications per year

2017–2026

14

Variants

Presequence-dependent Mitochondrial Protein Import

Parents

Publications

80

[Protein import into mitochondria].

Zaĭtseva Lg, Ovchinnikova Tv, Grinkevich Va · PubMed · 2000 · 971 citations

, , +17

Structural Basis of Presequence Recognition by the Mitochondrial Protein Import Receptor Tom20

Yoshito Abe, Toshihiro Shodai, Takanori Muto et al. · Cell · 2000 · 586 citations · Full text

, , +13

Role of Tim23 as Voltage Sensor and Presequence Receptor in Protein Import into Mitochondria

Matthias Bauer, Christian Sirrenberg, Walter Neupert et al. · Cell · 1996 · 308 citations · Full text

, , +12

Tim50 Maintains the Permeability Barrier of the Mitochondrial Inner Membrane

Michael Meinecke, Richard Wagner, Peter Kovermann et al. · Science · 2006 · 204 citations

, , +17

Artificial mitochondrial presequences.

D S Allison, Gottfried Schatz · Proceedings of the National Academy of Sciences · 1986 · 201 citations · Full text

, , +10

1–5 of 80

Authors

329

  1. BG
    Bernard Guiard

    Centre de Génétique Moléculaire, France

    12 publications · 1.1K citations

    12

    h-index

  2. PR
    Peter Rehling

    University of Göttingen, Germany

    11 publications · 1.1K citations

    11

    h-index

  3. NP
    Nikolaus Pfanner

    University of Freiburg, Germany

    10 publications · 1K citations

    10

    h-index

  4. MV
    Martin van der Laan

    University of Freiburg, Germany

    8 publications · 618 citations

    8

    h-index

  5. WN
    Walter Neupert

    Ludwig-Maximilians-Universität München, Germany

    8 publications · 743 citations

    8

    h-index

1–5 of 329

Institutions

102

  1. University of Freiburg

    Freiburg im Breisgau, Germany

    16 h-index

    92 publications

    9K citations

  2. Centre de Génétique Moléculaire

    Gif-sur-Yvette, France

    12 h-index

    22 publications

    3.1K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    32 publications

    3.3K citations

  4. Ludwig-Maximilians-Universität München

    Munich, Germany

    9 h-index

    30 publications

    2.9K citations

  5. Nagoya University

    Nagoya, Japan

    7 h-index

    36 publications

    6K citations

  6. University of Göttingen

    Göttingen, Germany

    7 h-index

    37 publications

    2.2K citations

  7. Max Planck Institute for Biophysical Chemistry

    Göttingen, Germany

    6 h-index

    10 publications

    620 citations

  8. Universitätsmedizin Göttingen

    Göttingen, Germany

    6 h-index

    35 publications

    2.1K citations

1–8 of 102

Venues

  1. Journal of Biological Chemistry

    JBC · 23 publications · 1.6K citations

    22

    h-index

  2. Molecular and Cellular Biology

    MCB · 6 publications · 440 citations

    6

    h-index

  3. The Journal of Cell Biology

    JCB · 5 publications · 496 citations

    5

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 447 citations

    4

    h-index

  5. Scientific Reports

    4 publications · 136 citations

    4

    h-index

1–5