Concepedia

Preclinical Research

Preclinical Research is a foundational phase of translational medicine that involves systematic laboratory and animal-based studies designed to evaluate the biological activity, safety, and efficacy of potential therapeutic interventions prior to their testing in human clinical trials.

333

Publications

29.8K

Citations

1.3K

Authors

603

Institutions

Publications per year

2017–2026

88

Variants

Preclinical Studies

Parents

Children

Publications

333

Raise standards for preclinical cancer research

C. Glenn Begley, Lee M. Ellis · Nature · 2012 · 2.9K citations · Full text

, , +12

Advances in Experimental Medicine and Biology

G.G. Lunt · Neurochemistry International · 1986 · 1.9K citations

, , +12

Can Animal Models of Disease Reliably Inform Human Studies?

H. Bart van der Worp, David W. Howells, Emily S. Sena et al. · PLoS Medicine · 2010 · 1.3K citations · Full text

, , +16

Humanized mice in translational biomedical research

Leonard D. Shultz, Fumihiko Ishikawa, Dale L. Greiner · Nature reviews. Immunology · 2007 · 1.3K citations

, , +7

The Economics of Reproducibility in Preclinical Research

Leonard P. Freedman, Iain Cockburn, Timothy Simcoe · PLoS Biology · 2015 · 1.1K citations · Full text

, , +11

1–5 of 333

Authors

1.3K

  1. MR
    Merel Ritskes‐Hoitinga

    Radboud University Nijmegen, Netherlands

    10 publications · 717 citations

    10

    h-index

  2. MM
    Malcolm Macleod

    University of Edinburgh, United Kingdom

    8 publications · 1.9K citations

    8

    h-index

  3. ES
    Emily S. Sena

    University of Edinburgh, United Kingdom

    5 publications · 1.7K citations

    5

    h-index

  4. UD
    Ulrich Dirnagl

    Charité - Universitätsmedizin Berlin, Germany

    6 publications · 439 citations

    5

    h-index

  5. JK
    Jonathan Kimmelman

    McGill University, Canada

    4 publications · 364 citations

    4

    h-index

1–5 of 1.3K

Institutions

603

  1. Radboud University Nijmegen

    Nijmegen, The Netherlands

    15 h-index

    32 publications

    2.1K citations

  2. National Institutes of Health

    Bethesda, United States

    13 h-index

    21 publications

    1.3K citations

  3. Radboud University Medical Center

    Nijmegen, The Netherlands

    13 h-index

    22 publications

    1.8K citations

  4. University of Edinburgh

    Edinburgh, United Kingdom

    11 h-index

    15 publications

    3.6K citations

  5. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    9 h-index

    26 publications

    991 citations

  6. Johns Hopkins University

    Baltimore, United States

    7 h-index

    40 publications

    6.2K citations

  7. Imperial College London

    London, United Kingdom

    7 h-index

    16 publications

    723 citations

  8. Ludwig-Maximilians-Universität München

    Munich, Germany

    6 h-index

    17 publications

    633 citations

1–8 of 603

Venues

  1. PubMed

    Repository · 14 publications · 485 citations

    12

    h-index

  2. PLoS Biology

    10 publications · 2.1K citations

    10

    h-index

  3. Journal of Translational Medicine

    JTM · 7 publications · 783 citations

    7

    h-index

  4. Science Translational Medicine

    STM · 7 publications · 293 citations

    7

    h-index

  5. Clinical Pharmacology & Therapeutics

    CPT · 6 publications · 341 citations

    6

    h-index

1–5