Concepedia

Pre-steady-state Kinetics

Pre-Steady-State Kinetics is a kinetic analysis method in enzyme catalysis that examines the transient phase of a reaction immediately after its initiation, before the concentrations of intermediates reach a steady state, to elucidate catalytic mechanisms and rate-limiting steps at the molecular level.

653

Publications

30.2K

Citations

2K

Authors

565

Institutions

Publications per year

2017–2026

52

Variants

Pre-steady State Kinetics

Parents

Publications

653

Human Placenta Thioredoxin Reductase

Stephan Gromer, L. David Arscott, Charles H. Williams et al. · Journal of Biological Chemistry · 1998 · 535 citations · Full text

, , +15

Mechanism of Inhibition of HIV-1 Reverse Transcriptase by Nonnucleoside Inhibitors

Rebecca Spence, Warren M. Kati, Karen S. Anderson et al. · Science · 1995 · 522 citations · Full text

, , +17

Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant

Smita S. Patel, Isaac Wong, Kenneth A. Johnson · Biochemistry · 1991 · 498 citations

, , +10

The mechanism of action of superoxide dismutase from pulse radiolysis and electron paramagnetic resonance. Evidence that only half the active sites function in catalysis

E.M. Fielden, Peter Roberts, Robert C. Bray et al. · Biochemical Journal · 1974 · 353 citations · Full text

, , +17

On the mathematical status of the pseudo-steady state hypothesis of biochemical kinetics

F.G. Heineken, H. M. Tsuchiya, R. Aris · Mathematical Biosciences · 1967 · 295 citations

, , +15

1–5 of 653

Authors

2K

  1. KS
    Karen S. Anderson

    Yale University, United States

    16 publications · 1.1K citations

    15

    h-index

  2. FP
    F. Peter Guengerich

    Vanderbilt University, United States

    11 publications · 699 citations

    11

    h-index

  3. KA
    Kenneth A. Johnson

    The University of Texas at Austin, United States

    12 publications · 1.1K citations

    10

    h-index

  4. ZS
    Zucai Suo

    The Ohio State University, United States

    11 publications · 517 citations

    10

    h-index

  5. NA
    Nikita A. Kuznetsov

    Institute of Chemical Biology and Fundamental Medicine, Russia

    10 publications · 390 citations

    10

    h-index

1–5 of 2K

Institutions

565

  1. Yale University

    New Haven, United States

    21 h-index

    30 publications

    1.7K citations

  2. The Ohio State University

    Columbus, United States

    19 h-index

    23 publications

    1.3K citations

  3. Pennsylvania State University

    State College, United States

    17 h-index

    18 publications

    2.4K citations

  4. University of Michigan

    Ann Arbor, United States

    14 h-index

    14 publications

    1K citations

  5. Vanderbilt University

    Nashville, United States

    14 h-index

    14 publications

    837 citations

  6. Albert Einstein College of Medicine

    Bronx, United States

    12 h-index

    13 publications

    586 citations

  7. National Institutes of Health

    Bethesda, United States

    12 h-index

    13 publications

    410 citations

  8. University of Pittsburgh

    Pittsburgh, United States

    11 h-index

    11 publications

    548 citations

1–8 of 565

Venues

  1. Biochemistry

    251 publications · 12.1K citations

    62

    h-index

  2. Journal of Biological Chemistry

    JBC · 108 publications · 6K citations

    45

    h-index

  3. Biochemical Journal

    BJ · 28 publications · 1.9K citations

    21

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 18 publications · 1.5K citations

    18

    h-index

  5. Journal of the American Chemical Society

    JACS · 16 publications · 673 citations

    15

    h-index

1–5