Concepedia

Pre-initiation Complex Assembly

Pre-Initiation Complex Assembly is a molecular event in the transcription cycle that constitutes the stepwise formation of a multi-protein machinery at the core promoter, wherein general transcription factors and RNA Polymerase II are sequentially recruited and stabilized to position the polymerase for accurate initiation of transcription.

177

Publications

12.6K

Citations

878

Authors

295

Institutions

Publications per year

2017–2026

45

Variants

Pic Assembly

Parents

Publications

177

Genome-wide structure and organization of eukaryotic pre-initiation complexes

Ho Sung Rhee, B. Franklin Pugh · Nature · 2012 · 542 citations

, , +14

Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequences

Barry L. Davison, Jean‐Marc Egly, Eileen R. Mulvihill et al. · Nature · 1983 · 471 citations

, , +15

Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex

Masami Horikoshi, Tsonwin Hai, Young-Sun Lin et al. · Cell · 1988 · 465 citations

, , +16

Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II

Wilma A. Hofmann, Ljuba Stojiljković, Beata Fuchsová et al. · Nature Cell Biology · 2004 · 364 citations

, , +14

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

Julie H. Cocker, Simonetta Piatti, Corrado Santocanale et al. · Nature · 1996 · 358 citations

, , +16

1–5 of 177

Authors

878

  1. PC
    Patrick Cramer

    Max Planck Institute for Biophysical Chemistry, Germany

    10 publications · 823 citations

    10

    h-index

  2. SS
    S. Schilbach

    Max Planck Institute for Biophysical Chemistry, Germany

    7 publications · 674 citations

    7

    h-index

  3. RG
    Robert G. Roeder

    Rockefeller University, United States

    6 publications · 1K citations

    6

    h-index

  4. CD
    Christian Dienemann

    Max Planck Institute for Biophysical Chemistry, Germany

    5 publications · 541 citations

    5

    h-index

  5. YH
    Yuan He

    Northwestern University, United States

    4 publications · 652 citations

    4

    h-index

1–5 of 878

Institutions

295

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    14 h-index

    26 publications

    3.3K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    12 h-index

    69 publications

    4.9K citations

  3. Inserm

    Paris, France

    10 h-index

    49 publications

    3.8K citations

  4. Rockefeller University

    New York, United States

    8 h-index

    19 publications

    3.3K citations

  5. Harvard University

    Cambridge, United States

    8 h-index

    16 publications

    2.6K citations

  6. Max Planck Institute for Biophysical Chemistry

    Göttingen, Germany

    7 h-index

    29 publications

    3.5K citations

  7. Institut de génétique et de biologie moléculaire et cellulaire

    Illkirch-Graffenstaden, France

    7 h-index

    34 publications

    1.7K citations

  8. National Institutes of Health

    Bethesda, United States

    6 h-index

    26 publications

    2K citations

1–8 of 295

Venues

  1. Nucleic Acids Research

    31 publications · 1.2K citations

    21

    h-index

  2. Journal of Biological Chemistry

    JBC · 13 publications · 733 citations

    13

    h-index

  3. Nature Communications

    10 publications · 542 citations

    10

    h-index

  4. Nature

    10 publications · 2.8K citations

    10

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 714 citations

    10

    h-index

1–5