Concepedia

Prdm9 Binding Sites

PRDM9 Binding Sites is a genomic locus category defined as a specific DNA sequence motif recognized and bound by the PRDM9 protein, a zinc-finger histone methyltransferase that directs meiotic recombination to hotspot regions through sequence-specific binding and chromatin modification.

39

Publications

5K

Citations

199

Authors

84

Institutions

Publications per year

2017–2026

14

Parents

Publications

39

PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice

Frédéric Baudat, Jérôme Buard, Corinne Grey et al. · Science · 2009 · 1.1K citations · Full text

, , +14

Drive Against Hotspot Motifs in Primates Implicates the <i>PRDM9</i> Gene in Meiotic Recombination

Simon Myers, Rory Bowden, Afidalina Tumian et al. · Science · 2009 · 719 citations

, , +15

Stable recombination hotspots in birds

Sonal Singhal, Ellen M. Leffler, Keerthi Sannareddy et al. · Science · 2015 · 397 citations · Full text

, , +17

PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans

Ingrid Berg, Rita Neumann, Kwan-Wood Gabriel Lam et al. · Nature Genetics · 2010 · 332 citations · Full text

, , +12

Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice

Benjamin Davies, Edouard Hatton, Nicolas Altemose et al. · Nature · 2016 · 233 citations · Full text

, , +9

1–5 of 39

Authors

199

  1. BD
    Bernard de Massy

    Institut de Génétique Humaine, France

    6 publications · 1.6K citations

    6

    h-index

  2. PM
    Petko M. Petkov

    Jackson Laboratory, United States

    6 publications · 521 citations

    6

    h-index

  3. MP
    Molly Przeworski

    Columbia University, United States

    5 publications · 1.6K citations

    5

    h-index

  4. KP
    Kenneth Paigen

    Roswell Park Comprehensive Cancer Center, United States

    5 publications · 474 citations

    5

    h-index

  5. SM
    Simon Myers

    University of Oxford, United Kingdom

    5 publications · 1.2K citations

    5

    h-index

1–5 of 199

Institutions

84

  1. University of Oxford

    Oxford, United Kingdom

    8 h-index

    53 publications

    10.3K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    32 publications

    7.3K citations

  3. Centre for Human Genetics

    Oxford, United Kingdom

    7 h-index

    51 publications

    10.1K citations

  4. Institut de Génétique Humaine

    Montpellier, France

    6 h-index

    28 publications

    6.7K citations

  5. Jackson Laboratory

    Bar Harbor, United States

    6 h-index

    46 publications

    4.2K citations

  6. Columbia University

    New York, United States

    5 h-index

    18 publications

    1.7K citations

  7. National Institutes of Health

    Bethesda, United States

    5 h-index

    13 publications

    519 citations

  8. Université Claude Bernard Lyon 1

    Villeurbanne, France

    4 h-index

    9 publications

    659 citations

1–8 of 84

Venues

  1. Science

    4 publications · 2.2K citations

    4

    h-index

  2. eLife

    3 publications · 168 citations

    3

    h-index

  3. PLoS Genetics

    3 publications · 334 citations

    3

    h-index

  4. Genome Research

    GR · 3 publications · 181 citations

    3

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 165 citations

    2

    h-index

1–5